Effects of electrical stimulation on diaphragm function

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the efficacy of transcutaneous electrical phrenic nerve stimulation (TEPNS) and transcutaneous electrical diaphragm stimulation (TEDS) in healthy adults. Participants aged 18 to 60 with a normal BMI will undergo a crossover design where they will receive both TEPNS and TEDS interventions. The diaphragm's muscle characteristics will be assessed using ultrasound, and the study will also gather data on the feasibility, safety, and discomfort associated with these stimulation techniques. The trial is conducted at two hospitals in a single-blind format.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 60 years;
* Normal pulmonary function test, without alterations, assessed through spirometry;
* Body Mass Index (BMI) between 18.5 and 24.9 kg/m2.

Exclusion Criteria:

* Smokers or former smokers;
* Individuals with previously known cardiopulmonary diseases (restrictive lung diseases, chronic obstructive pulmonary disease - COPD, asthma, cystic fibrosis, among other pathologies);
* Presence of implanted electrical devices (pacemaker, implantable cardioverter-defibrillator, among others);
* Individuals who have contraindications to undergo evaluation and/or application of transcutaneous electrical stimulation of the diaphragm muscle, such as: altered sensitivity, wounds at the site of application, deformities, among other conditions.

Where it's running

• Hospital Sírio Libanês
  São Paulo, São Paulo, Brazil Recruiting

Study contacts

• Study coordinator: RENATO F RIGHETTI, PhD
• Email: refragar@gmail.com
• Phone: 11987496664

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.