Effects of eating timing and quantity on metabolism and inflammation

ChronoMet: Metabolic and Inflammatory Effects of Eating Timing and Quantity

NA · University of Minnesota · NCT06161337

This study looks at how overeating, especially in the evening, affects metabolism and inflammation to help find better ways to manage overeating and its health effects.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversity of Minnesota (other)
Locations1 site (Minneapolis, Minnesota)
Trial IDNCT06161337 on ClinicalTrials.gov

What this trial studies

This observational study investigates how acute overeating affects metabolic and inflammatory responses, particularly focusing on the timing of calorie intake. The researchers hypothesize that consuming excess calories, especially in the evening, may lead to increased inflammation and metabolic dysfunction. By analyzing the biological consequences of overeating, the study aims to provide insights that could inform new strategies to address overeating and its health impacts.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy adults aged 18-65 with a normal BMI and no comorbid conditions.

Not a fit: Patients who are pregnant or have comorbid conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved dietary guidelines and interventions to mitigate the negative health effects of overeating.

How similar studies have performed: While the specific approach of this study may be novel, previous research has indicated that meal timing and quantity can significantly impact metabolic health.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ages of 18-65 years old
* not pregnant
* no comorbid conditions
* normal BMI (18.5 - 24.9 kg/m2)
* Weight ≥120 lbs self-reported weight

Exclusion Criteria:

* N/A

Where this trial is running

Minneapolis, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Healthy Volunteers

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.