Effects of eating eggs on metabolism and liver health in obese individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research investigates how consuming three eggs daily impacts metabolic health and liver function in individuals with obesity. The study focuses on the role of choline, a nutrient found in eggs, in lipid metabolism and its potential effects on liver health. Participants will follow a controlled diet for four weeks, during which their metabolic outcomes, including liver enzymes and body composition, will be monitored. The study aims to understand individual variations in response to egg intake based on gut microbiota composition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female participant of any race or ethnicity between 30-65 (inclusive) years of age
* BMI \> 30 kg/m2
* Non-smoker
* Willing to consume 3 eggs per day for one dietary period of 4 weeks
* Willing to avoid eggs during the rest of the study except for eggs that are provided
* Willing to follow the study protocol including maintaining usual lifestyle during the entire study

Exclusion Criteria:

* Age \< 30 or \> 65 years
* BMI \< 30 kg/m2
* Vegans or individuals who do not consume eggs
* Individuals who are currently pregnant or planning to become pregnant during the course of the study; or are currently breastfeeding
* Smokers, users of recreational drugs
* Individuals taking antibiotics or natural health products including prebiotics or probiotics

Where it's running

• Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec - ULaval
  Québec, Quebec, Canada Recruiting

Study contacts

• Study coordinator: Clara E. Cho, PhD
• Email: claracho@uoguelph.ca
• Phone: (519) 824-4120

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.