Effects of early mobilization on recovery in ICU patients with sepsis
The Influences of Duration and Intensity of Early Mobilization on Myokines, Body Composition and Outcomes of Septic Patients in Intensive Care Unit
This study tests if starting physical therapy early helps ICU patients with sepsis recover better by looking at changes in their body and muscle-related proteins.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 600 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Locations | 1 site (Kaohsiung City) |
| Trial ID | NCT06061224 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of early physical therapy on septic patients in the ICU, focusing on how it influences myokines and body composition. Patients will be divided into three groups: one receiving no physical therapy, one starting therapy on day 3, and another starting after day 3. The study aims to measure changes in body composition and myokine levels over time to understand their relationship with patient outcomes. The findings could inform future precision medicine approaches for treating sepsis.
Who should consider this trial
Good fit: Ideal candidates are ICU patients diagnosed with sepsis who can participate in physical therapy.
Not a fit: Patients who are expected to expire within three days or have certain medical devices or diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and reduced hospital stays for patients with sepsis.
How similar studies have performed: Other studies have shown promising results with early mobilization in ICU patients, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1. Aadmission in ICU 2. Clinical diagnosis of sepsis Exclusion Criteria: * 1. Expired in 3-days 2. Cardiac stents or pacemakers 3. Airborne disease 4. Contact-transmitted disease
Where this trial is running
Kaohsiung City
- Kaohsiung Chang Gung Memorial Hospital — Kaohsiung City, Taiwan (Recruiting)
Study contacts
- Principal investigator: Fang Wen-Feng — Chang Gung Memorial Hospital
- Study coordinator: Fang Wen-Feng
- Email: wenfengfang@yahoo.com.tw
- Phone: +886 7 731 7123
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.