Effects of different training environments on post-covid-19 athletes' immune and metabolic responses
Influence of Physical Training Protocols in Hypoxic, Normobaric and Hypobaric Environments, on the Immune, Metabolic Response and Cardiopulmonary Behavior in Athletes Convalescent From Covid-19
This study tests how different training environments, like low oxygen levels, affect the immune system and metabolism in athletes recovering from COVID-19.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 30 Years |
| Sex | All |
| Sponsor | Faculdade de Motricidade Humana Academic / other |
| Locations | 1 site (Lisbon) |
| Trial ID | NCT06128941 on ClinicalTrials.gov |
What this trial studies
This study investigates how hypoxic, normobaric, and hypobaric training affects the immune and metabolic responses in athletes recovering from COVID-19. It aims to evaluate the impact of these training protocols on cardiopulmonary behavior and identify potential biomarkers related to exercise and immunometabolism. Participants will be divided into groups performing repeated sprints under different oxygen conditions, including a control group training in normal oxygen levels. The study combines randomized controlled interventions with observational assessments at natural altitude to provide comprehensive insights into the effects of hypoxia on athletic recovery post-COVID-19.
Who should consider this trial
Good fit: Ideal candidates include athletes with over 5 years of training experience who are recovering from COVID-19 and regularly participate in national or international competitions.
Not a fit: Patients who have had recent altitude acclimatization, are currently symptomatic of COVID-19, or are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance recovery strategies for athletes post-COVID-19, improving their overall health and performance.
How similar studies have performed: While the specific combination of hypoxic training and post-COVID-19 recovery is novel, similar studies have shown positive outcomes in using hypoxia to enhance athletic performance and recovery.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * more than 5 years of training experience in an resistance modality; * participates in national or international championships regularly; * athletes convalescing from covid-19, at least 30 days after diagnosis and/or hospital discharge; * manifested mild to severe symptoms; * vaccinated or not against SARS-CoV-2; * antigen self-test for SARS-CoV-2 negative. Exclusion Criteria: * athletes who have had an acclimatization experience or exposure to altitude lasting more than 10 days in the last 6 months; * contain signs or symptoms of acute covid-19; * present a positive SARS-CoV-2 antigen self-test; * pregnant or postpartum women; * use anti-inflammatory or immunosuppressive medications.
Where this trial is running
Lisbon
- Faculty of Human Kinetics — Lisbon, Portugal (Recruiting)
Study contacts
- Study coordinator: Cristina Monteiro, PhD
- Email: cmonteiro@fmh.ulisboa.pt
- Phone: 00351214149174
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.