Effects of different concentrations of ropivacaine on ankle blocks for foot surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates how varying concentrations of ropivacaine (0.25%, 0.5%, and 1%) affect the onset time and duration of ultrasound-guided ankle blocks in patients undergoing forefoot surgery for hallux valgus repair. The research aims to determine whether higher concentrations lead to faster onset and longer sensory block duration, which could improve postoperative analgesia. Primary outcomes include the duration of sensory blocks, while secondary outcomes assess onset time, motor function, pain scores, opioid consumption, and block failure rates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Provide signed and dated informed consent
* Age 18 up to and including 75 years, scheduled for elective forefoot surgery for hallux valgus repair, with or without one or more of the following: minor toe procedures, osteotomies, arthrodesis or toe extensor/flexor procedures, under unilateral ankle block at ZOL Genk
* ASA physical I-II-III
* Able to ambulate (ability to walk independently, with or without assistive devices)
* Able to learn and perform study sensory and motor assessment by exhibiting sensitivity to pinprick, cold, and light touch (tested beforehand with pinprick/cold/ light touch sensation test) as the patient will have to perform these sensory and motor assessments by him/herself at home at postoperative day 0 to 2

Exclusion Criteria:

* Language barrier
* Preexisting lower extremity neuropathy
* Contraindications to ankle block (local infection, edema, burn, soft tissue trauma, or distorted anatomy with scarring in the area of block placement)
* Contraindications for use of NSAIDs
* Allergy to local anesthetics
* Uncontrolled anxiety, psychiatric or neurological disorder that might interfere with study assessment
* Weight below 50 kg based on a maximum dose of 3 mg/kg ropivacaine and a maximum dose of 150 mg ropivacaine.
* Preoperative use of opioids or gabapentin less than 3 days before surgery
* Contraindications for use of paracetamol
* Contraindications for use of tramadol

Where it's running

• Ziekenhuis Oost-Limburg
  Genk, Limburg, Belgium Recruiting

Study contacts

• Study coordinator: Imré Van Herreweghe, MD
• Email: imrevanherreweghe@gmail.com
• Phone: +32474661273

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.