Effects of diet and exercise on appetite and body composition in overweight women
Role of Gastrointestinal Appetite Hormones in the Success of Body Mass Loss Interventions Based on Exercise Combined With Calorie-restricted Diets With Different Fat and Carbohydrate Content
NA · University of Glasgow · NCT06022315
This study is testing how different diets and exercise routines can change appetite and body composition in overweight women.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 25 Years to 45 Years |
| Sex | Female |
| Sponsor | University of Glasgow (other) |
| Locations | 1 site (Glasgow) |
| Trial ID | NCT06022315 on ClinicalTrials.gov |
What this trial studies
This study investigates how different macronutrient compositions in energy-restricted diets, combined with exercise training, affect appetite hormones, subjective appetite, and energy intake in overweight and obese women. Participants will be randomly assigned to either a high-carbohydrate low-fat diet or a low-carbohydrate high-fat diet, both paired with an exercise program over four weeks. Measurements of body composition, appetite hormones, and insulin levels will be taken before and after the intervention, alongside dietary intake records to assess changes in calorie consumption. The study aims to understand the interactions between diet, exercise, and metabolic risk factors for cardiovascular diseases.
Who should consider this trial
Good fit: Ideal candidates are healthy women with a BMI of 25.0 kg/m2 or higher who have maintained stable body weight for at least three months.
Not a fit: Patients who smoke, have irregular menstrual cycles, or are on medications or specific diets may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into effective dietary strategies for weight management and appetite regulation in overweight women.
How similar studies have performed: Previous studies have shown promising results in the effects of diet composition and exercise on appetite and metabolic health, suggesting this approach has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy Female * BMI of ≥25.0 kg/m2. * stable body weight for at least three months preceding the study Exclusion Criteria: * smokers and have * irregular menstruation cycle, * use any type of medication, * exercising more than 75min a week, * are pregnant or lactating. * on any dietary supplements at the time of the study, * are vegetarian or are following any diet other than the typical Western diet.
Where this trial is running
Glasgow
- Human Nutrition, College of Medicine, Veterinary and Life Science — Glasgow, United Kingdom (RECRUITING)
Study contacts
- Principal investigator: Taibah Almesbehi — University of Glasgow, New lister Building, Glasgow, Scotland, United kingdom, G31 2ER
- Study coordinator: Dr Dalia Malkova
- Email: Dalia.Malkova@glasgow.ac.uk
- Phone: 01412018690
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastrointestinal Hormones