Effects of creatine supplementation on muscle performance in young adults
Effects of Equal-volume Creatine Supplementation With Different Dosing Strategies on Body Composition and Muscle Performance in Young Healthy Adults
This study tests which way of taking creatine—either all at once or in smaller doses over time—helps young adults build muscle and improve their strength and endurance better than a placebo.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 42 (estimated) |
| Ages | 18 Years to 39 Years |
| Sex | All |
| Sponsor | University of Regina Academic / other |
| Locations | 1 site (Regina, Saskatchewan) |
| Trial ID | NCT06604793 on ClinicalTrials.gov |
What this trial studies
This study compares the effects of two different creatine supplementation protocols—bolus ingestion and intermittent ingestion—against a placebo over a 21-day period. Participants will be assessed for changes in body composition, including lean tissue mass and total body water, as well as muscle performance metrics such as power, strength, and endurance. The goal is to determine the most effective method of creatine supplementation for enhancing muscle performance in young healthy adults.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy young adults aged 18-39 who have not engaged in resistance training for at least four weeks prior to participation.
Not a fit: Patients who are pregnant, nursing, or have recently taken creatine monohydrate may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimal creatine supplementation strategies to improve muscle performance in young adults.
How similar studies have performed: Previous studies have shown that creatine supplementation can improve muscle performance, but the specific protocols being tested in this study are less explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * if you are 18-39 years of age * if you have not been performing resistance training for at least 4 weeks prior to the start of the study. Exclusion Criteria: * if you are pregnant or nursing * have taken creatine monohydrate within 30 days prior to the start of the study * if you have pre-existing allergies to the placebo (corn-starch maltodextrin)
Where this trial is running
Regina, Saskatchewan
- University of Regina — Regina, Saskatchewan, Canada (Recruiting)
Study contacts
- Principal investigator: Darren Candow — University of Regina
- Study coordinator: Darren Candow
- Email: Darren.Candow@uregina.ca
- Phone: 306-585-4906
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.