Effects of creatine supplementation on heart and blood vessel function in older men
Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men
This study tests if taking creatine, with or without some exercise, can improve heart and blood vessel function in older men.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 45 (estimated) |
| Ages | 55 Years to 80 Years |
| Sex | Male |
| Sponsor | Radford University Academic / other |
| Locations | 1 site (Roanoke, Virginia) |
| Trial ID | NCT05329480 on ClinicalTrials.gov |
What this trial studies
This study investigates how creatine supplementation, either alone or combined with moderate physical activity, affects vascular reactivity and heart hemodynamics in elderly men. Participants will undergo baseline testing to assess their cardiovascular health and will be monitored during a submaximal exercise test. Heart function will be measured using a non-invasive bioimpedance device and ECG, while vascular responses will be evaluated with arterial pulse wave velocity equipment. The study aims to provide insights into the potential benefits of creatine for improving cardiac function in older adults.
Who should consider this trial
Good fit: Ideal candidates for this study are males aged 55 to 80 who are appropriate for moderate intensity exercise.
Not a fit: Patients with serious cardiac or kidney pathologies, or those outside the age range, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of how creatine supplementation may improve heart and vascular health in elderly men.
How similar studies have performed: While there is limited research specifically on creatine's effects in elderly populations, similar studies on younger adults have shown promising results regarding its impact on muscle and cardiovascular health.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Males * 55-80 years old * No restrictions based on race, ethnicity, or socioeconomic status Exclusion Criteria: * Females * \<55 or \>80 years old * Individuals with known serious cardiac pathology * Individuals with known serious kidney pathology * Appropriate for moderate intensity exercise (screening using PAR-Q+) * Individuals currently consuming or had consumed creatine supplement within 3 months prior to screening
Where this trial is running
Roanoke, Virginia
- Carilion Roanoke Community Hospital — Roanoke, Virginia, United States (Recruiting)
Study contacts
- Study coordinator: Adrian Aron
- Email: aaron@radford.edu
- Phone: 5402246665
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.