Effects of creatine supplementation and resistance training on muscle growth in young adults

Strategic Ingestion of Creatine Supplementation and Resistance Training in Trained Young Adults

Not applicable Interventional University of Regina · NCT06438887

This study tests whether taking creatine before, during, or after workouts helps young adults build more muscle and improve their performance while doing resistance training.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment52 (estimated)
Ages18 Years to 39 Years
SexAll
SponsorUniversity of Regina Academic / other
Locations2 sites (Regina, Saskatchewan and 1 other locations)
Trial IDNCT06438887 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of different timing strategies for creatine supplementation during a resistance training program on muscle growth and performance in young adults. Participants will be physically active individuals aged 18-39 who engage in structured resistance training at least twice a week. The study will compare the effects of creatine monohydrate versus a placebo, focusing on whether taking creatine before, during, or after workouts yields the best results. The goal is to determine the optimal creatine ingestion protocol to maximize muscle accretion and performance improvements.

Who should consider this trial

Good fit: Ideal candidates for this study are physically active males and females aged 18-39 who perform structured resistance training at least twice a week.

Not a fit: Patients who are pregnant or nursing, have consumed creatine monohydrate recently, or have allergies to the placebo may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into the most effective creatine supplementation strategies to enhance muscle growth and performance for young adults engaged in resistance training.

How similar studies have performed: Previous studies have shown that creatine supplementation can enhance muscle benefits in older adults, but this specific approach in young adults is novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Physically active (performing structured resistance training \> 2x/week for ≥ 4 weeks)
* Males and females (age 18-39)

Exclusion Criteria:

* Pregnant or nursing
* Have consumed creatine monohydrate within 30 days prior to the start of the study
* Pre-existing allergies to the placebo

Where this trial is running

Regina, Saskatchewan and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrengthMuscle
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.