Effects of cognitive-motor exercise on brain activity in stroke patients
Using Functional Near-infrared Spectroscopy to Study the Changes in Brain Activity During Dual-task Walking and the Effects of Structured Cognitive-motor Exercise in Individuals With Stroke
This study tests if a special exercise program that combines walking with thinking tasks can help stroke patients improve their mobility and brain activity.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT06129227 on ClinicalTrials.gov |
What this trial studies
This study assesses how a dual-task exercise program impacts cognitive-motor interference during walking in stroke patients and examines the associated changes in brain activity. Stroke is a leading cause of chronic disability, and restoring mobility is crucial for rehabilitation. The program involves dual-task training, single-task training, and a control group to evaluate the effectiveness of these interventions. Participants will be monitored for their ability to perform mobility tasks while engaging in cognitive tasks, which is essential for community living.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50 and older who have experienced a stroke at least six months prior and can walk independently.
Not a fit: Patients with other neurological disorders or significant comorbidities affecting mobility may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance rehabilitation strategies for stroke patients, improving their mobility and daily functioning.
How similar studies have performed: There is increasing evidence supporting the effectiveness of dual-task training in improving mobility and cognitive function in stroke patients, indicating that this approach has shown promise in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of stroke confirmed by brain scan reports * Community-living * Stroke onset ≥ 6 months * Aged 50 years or older * Modified Rankin scale 1-3 * Capable of following verbal instructions * Montreal Cognitive Assessment score ≥ 22 * Ability to walk for 1 min independently with or without a walking aid * Not receiving formal rehabilitation elsewhere Exclusion Criteria: * Other neurological disorders * Pain or other comorbidities that seriously affect the ability to walk * Contraindications to exercise (e.g., angina).
Where this trial is running
Hong Kong
- The Hong Kong Polytechnic University — Hong Kong, Hong Kong (Recruiting)
Study contacts
- Principal investigator: Marco Yiu Chung PANG, PhD — The Hong Kong Polytechnic University
- Study coordinator: Marco Yiu Chung PANG, PhD
- Email: Marco.Pang@polyu.edu.hk
- Phone: 2766-7156
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.