Clinical trial No longer in our active list Interventional Ages 18 to 45

Effects of carbohydrate forms on running performance

Official title: Running Performance in Response to Different Forms of Carbohydrate

Run by University of Georgia · NCT06742398 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study tests whether using different forms of carbohydrates, like a mouth rinse or dissolvable strip, can help trained runners perform better in a 12.8 km race.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment50 (estimated)
SponsorUniversity of Georgia
Academic / other
Locations1 site (Athens, Georgia)
Trial IDNCT06742398 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are endurance-trained athletes aged 18-45 with a normal BMI who train regularly.

Probably not a fit

Patients on low carbohydrate diets or with chronic diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention examines how different forms of carbohydrates, specifically a carbohydrate mouth rinse and a dissolvable strip, influence running performance during a 12.8 km time trial. The study employs a randomized, controlled crossover design with endurance-trained athletes, who will participate in multiple testing visits where they will consume either a carbohydrate solution, a water solution, or a carbohydrate strip before running. The primary focus is to assess performance improvements and physiological responses, such as heart rate and blood lactate levels, while controlling for variables like menstrual cycle phases in female participants.

Why it matters

Potential benefit: If successful, this study could enhance athletic performance by identifying optimal carbohydrate delivery methods during exercise.

How similar studies have gone: Previous studies have shown positive effects of carbohydrate intake on exercise performance, suggesting this approach is supported by existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-45 years old
* Male or Female
* Normal body mass index (BMI) between 18.0-24.9kg/m2
* All subjects will be endurance-trained athletes who participate in training on a regular basis (≥4 sessions per week for at least 1 hour per session of aerobic/endurance exercise (such as running, cycling, or swimming)
* Women will be tested only during the follicular phase of their menstrual cycle (days 2-9) to control for any fluctuation in hormones
* Individuals aged 35 or older must pass the Physical Activity Readiness Questionnaire (PARQ2)

Exclusion Criteria:

* Anyone eating a low carbohydrate diet (such as The Zone™ Diet or Atkins™ Diet)
* Changes in current exercise program
* Chronic diseases (including but not limited to type II diabetes, hypertension, hypotension, hyperthyroidism, cardiovascular disease, and cancer)
* Medications that could alter metabolic rate or hydration status
* Supplement use other than fish oil or vitamin/mineral supplements
* Nicotine use
* Pregnancy or nursing
* Donation of blood in the 20 days prior to testing
* A failing result on the Physical Activity Readiness Questionnaire (PARQ2) for those aged 35 or older
* Allergy to red food dye FD\&C Red No. 40

Where it's running

  • University of Georgia
    Athens, Georgia, United States
    Recruiting

Study contacts

  • Principal investigator: Jamie A Cooper, Ph.D. — University of Georgia
  • Study coordinator: Jamie A Cooper, Ph.D.
  • Email: jamie.cooper@uga.edu
  • Phone: 706-542-4378

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.