Effects of carbohydrate feedings on gastrointestinal health in athletes
Hydrogen Breath Test Results After Consuming Fructose at Baseline and After Protein Supplementation
This study tests how different types of carbohydrate snacks affect gut health and breathing in athletes after hiking in the heat.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 5 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Arizona State University Academic / other |
| Locations | 1 site (Phoenix, Arizona) |
| Trial ID | NCT06648967 on ClinicalTrials.gov |
What this trial studies
This study investigates how different carbohydrate feedings impact hydrogen breath levels and gastrointestinal symptoms in healthy individuals after hiking in heat. Participants will undergo a treadmill hiking test followed by carbohydrate supplementation, with their hydrogen breath response and self-reported GI symptoms measured over time. The study aims to determine if varying carbohydrate ratios and a multi-ingredient whey supplement influence malabsorption and GI distress. Informed consent will be obtained before any study procedures commence.
Who should consider this trial
Good fit: Ideal candidates are healthy men and women aged 18-60 with a BMI between 18.5 and 30, who can perform daily activities independently.
Not a fit: Patients with diagnosed gastrointestinal disorders, lactose intolerance, or metabolic disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved dietary recommendations for athletes to enhance gastrointestinal health and performance.
How similar studies have performed: While there have been studies on carbohydrate malabsorption, this specific approach combining heat stress and supplementation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy subjects living in the United States. * Women/Men aged between 18-60 years (50-50%). * BMI value between ≥18.5 and ≤ 30 kg/m2. * No physical limitations (i.e., able to perform all activities associated with daily living in an independent manner). * Written informed consent. * Completed PAR-Q+ without any "yes" responses. * If currently using chronically or intermittently, willing to stop taking pre- and probiotics beginning 1 month prior to and throughout data collection. * If currently using chronically or intermittently, willing to stop using laxatives or fiber supplements, antacids and prokinetics beginning 1 month prior to and throughout data collection. Exclusion Criteria: * Smoking. * Clinical or self-perceived lactose intolerance. * Clinical or self-perceived milk protein allergy. * Diagnosed GI tract disorders or diseases. * Musculoskeletal disorders. * Diagnosed metabolic disorders (such as diabetes). * Use of any medications known to affect protein metabolism (i.e., corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications). * Chronic use of gastric acid suppressing medication or anti-coagulants. * Chronic use of anti-inflammatory medication. * Unwilling to stop taking pre- and probiotics beginning 1 month prior to and throughout data collection. * Unwilling to stop using laxatives or fiber supplements, antacids and prokinetics beginning 1 month prior to and throughout data collection.
Where this trial is running
Phoenix, Arizona
- Health Futures Center — Phoenix, Arizona, United States (Recruiting)
Study contacts
- Study coordinator: Floris Wardenaar, PhD
- Email: Floris.wardenaar@asu.edu
- Phone: 602-543-1853
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.