Effects of Cannabidiol on Learning and Anxiety in College Students
Official title: Cannabidiol Effects on Learning and Anxiety
Run by University of Connecticut · NCT05283382 · Data updated 2026-11-12
This study tests if a single dose of CBD can help college students with social anxiety feel less fear after a scary exercise.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | University of Connecticut Academic / other |
| Locations | 1 site (Storrs, Connecticut) |
| Status | Recruiting |
| Started | October 30, 2024 |
| Main results expected | December 30, 2026 |
| Study ends | February 2027 |
| Registry record updated | April 29, 2026 |
| Trial ID | NCT05283382 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are college students aged 18-50 who exhibit elevated levels of social anxiety.
✕Probably not a fit
Patients with heart problems, neurological disorders, or those currently using CBD or cannabis products may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates how Cannabidiol (CBD) may improve the extinction of fear responses in college students with elevated social anxiety. Participants will undergo a fear conditioning exercise where they learn to associate a face with a mild shock. Following this, half of the participants will receive a single dose of 600 mg CBD, while the other half will receive a placebo. The study will measure the effectiveness of CBD in reducing fear responses through physiological and subjective assessments.
Why it matters
Potential benefit: If successful, this study could provide a novel treatment option for individuals with social anxiety by enhancing their ability to overcome fear responses.
How similar studies have gone: While there is emerging research on CBD's effects on anxiety, this specific approach to fear conditioning extinction is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-50 years of age Exclusion Criteria: 1. Difficulties seeing a computer screen 2. Anyone currently taking CBD within the last 24 hours. 3. Anyone using any cannabis product within the last 24 hours. 4. Heart problems or heart disease 5. A neurological disorder such as epilepsy, stroke, multiple sclerosis, tumor, vascular malformations, aneurysm 6. Are currently pregnant or breast-feeding
Where it's running
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University of Connecticut
Storrs, Connecticut, United States Recruiting
Study contacts
- Study coordinator: Robert Astur, PhD
- Email: robert.astur@uconn.edu
- Phone: 2032369938
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.