Effects of caffeine on muscle twitching in healthy adults
Fasciculations in Healthy Adults After Consumption of Caffeine: an Ultrasound Study
This study is testing how caffeine affects involuntary muscle twitches in healthy adults aged 20-35 and 35-50.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Zurich Regional Health Center Academic / other |
| Locations | 1 site (Wetzikon, Zürich) |
| Trial ID | NCT05977920 on ClinicalTrials.gov |
What this trial studies
This study investigates the occurrence of muscle fasciculations, which are involuntary muscle contractions, in healthy adults after consuming caffeine. It aims to compare the frequency of these fasciculations in the muscles of the arms and legs across two age groups: 20-35 years and 35-50 years. A total of 52 participants will be recruited, with 26 individuals in each age group, to assess the differences in fasciculation occurrence using ultrasound techniques. The study will utilize a Fisher's exact test to analyze the data with a significance level of 0.05.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 20 to 50 years without any clinical neurological symptoms or other significant health issues.
Not a fit: Patients with existing neurological disorders or other serious health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of muscle responses to caffeine, potentially informing dietary recommendations for athletes and individuals with neuromuscular concerns.
How similar studies have performed: While there have been studies on fasciculations in healthy adults, this specific investigation into the effects of caffeine on muscle twitching is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Healthy subjects (male/female) * age 20-50 years old Exclusion criteria: * Clinical neurological symptoms * Clinical signs for Neuropathy * Clinical signs for Myopathy * Clinical signs for Vasculitis * Clinical signs for heart disease * Clinical signs for gastric or duodenal ulcera * Any medicine
Where this trial is running
Wetzikon, Zürich
- Gzo — Wetzikon, Zürich, Switzerland (Recruiting)
Study contacts
- Principal investigator: David Czell — Zurich Regional Health Center
- Study coordinator: David Czell, MD
- Email: david.czell@hin.ch
- Phone: +41764217222
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.