Effects of Buprenorphine, Clonidine, and Dexamethasone on Pain Management After Shoulder Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the impact of adding buprenorphine, clonidine, and dexamethasone to Interscalene brachial plexus blocks on postoperative pain management in patients undergoing shoulder arthroscopy. A total of 120 patients will be randomly assigned to receive either the enhanced block with adjuvants or the standard block alone. The primary outcome is to assess differences in morphine requirements post-surgery between the two groups. This prospective, randomized, single-blinded study seeks to determine if the addition of these medications can improve pain control.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients ≥ 18 years old
* Patients undergoing shoulder arthroscopy
* Patients willing to participate and sign informed consent

Exclusion Criteria:

* Severe COPD/other contraindication to general anesthesia
* Patient with a weight of less than 60 kg
* Dementia, not alert or oriented to person, place, or time
* Chronic pain patient with daily opioid use at home.
* Patient with allergy to local anesthetics
* Patient refusal
* Total shoulder arthroplasty
* Concomitant pain in different area from operative site.
* Pregnancy
* Patient with active infection on the injection sites for the blocks
* Patients unable or willing to understand or comply with the study protocol

Where it's running

• Loyola University Chicago
  Maywood, Illinois, United States Recruiting

Study contacts

• Principal investigator: Audrice Francois, MD — Loyola University Chicago
• Study coordinator: Susan Fargo
• Email: sfargo@luc.edu
• Phone: 708-216-8046

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.