Effects of breathing exercises on heart health in postmenopausal women

Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity On Normotensive Postmenopause Women : Randomized Clinical Trial

Not applicable Interventional Instituto de Cardiologia do Rio Grande do Sul · NCT03672760

This study tests if two different breathing exercises can help improve heart health in postmenopausal women who don't get much exercise.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages45 Years to 65 Years
SexFemale
SponsorInstituto de Cardiologia do Rio Grande do Sul Academic / other
Locations1 site (Porto Alegre, Rio Grande do Sul)
Trial IDNCT03672760 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of two different breathing exercise methods, Inspiratory Muscle Training (IMT) and the CardioBreath® App, on cardiovascular health in normotensive postmenopausal women. It aims to assess how these interventions influence cardiac vagal modulation and pulse wave velocity, which are indicators of autonomic nervous system function and vascular health. Participants will engage in either IMT or use the CardioBreath® App, which provides guided breathing exercises, to determine which method is more effective in improving cardiovascular outcomes. The study focuses on women who have been postmenopausal for at least 12 months and lead a sedentary lifestyle.

Who should consider this trial

Good fit: Ideal candidates are sedentary postmenopausal women with elevated follicle-stimulating hormone levels and at least 12 months of amenorrhea.

Not a fit: Patients with hypertension, diabetes, obesity, or other significant health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a non-invasive method to improve cardiovascular health in postmenopausal women.

How similar studies have performed: Previous studies have shown positive effects of respiratory exercises on cardiovascular health, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Follicle Stimulating Hormone (FSH)\>35mui/ml
* minimum 12 months amenorrhea
* sedentary life style (less than 150 minutes per week of exercise)

Exclusion Criteria:

* Hypertension
* Diabetes
* Obesity
* Use of Betablockers
* recent cardiovascular events or surgery
* renal alterations
* respiratory and/or motor pathologies
* smoking
* BMI\>29,9

Where this trial is running

Porto Alegre, Rio Grande do Sul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postmenopausal DisorderAutonomic ImbalanceVascular Stiffness
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.