Effects of brain stimulation on cognitive control and attention

Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands

Not applicable Interventional University of California, Davis · NCT04885322

This study is testing whether a type of brain stimulation can improve attention and thinking skills in healthy people by comparing the effects of stimulating different areas of the brain.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment75 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorUniversity of California, Davis Academic / other
Locations1 site (Sacramento, California)
Trial IDNCT04885322 on ClinicalTrials.gov

What this trial studies

This study investigates how transcranial direct current stimulation (tDCS) affects cognitive control and attention in healthy individuals. By applying tDCS to specific areas of the scalp, researchers aim to understand the neural mechanisms involved in higher-order cognitive processes such as language comprehension and memory. Participants will undergo cognitive tasks while their performance is measured through behavioral assessments and EEG recordings. The study compares the effects of stimulating the prefrontal cortex versus the occipital cortex to determine which area enhances cognitive performance more effectively.

Who should consider this trial

Good fit: Ideal candidates are healthy adults aged 18 to 50 who can understand and complete cognitive tasks in English.

Not a fit: Patients with a history of head trauma, current or previous psychotropic medication treatment, or contraindications to tDCS will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to new non-invasive methods for enhancing cognitive function in various populations.

How similar studies have performed: Other studies have shown promising results with tDCS in enhancing cognitive functions, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* between ages of 18 and 50
* ability to sufficiently speak and understand English so as to be able to understand and complete cognitive tasks
* ability to give valid informed consent

Exclusion Criteria:

* no history of head trauma
* no current or previous history of treatment with psychotropic medication
* corrected vision 20/30 or better
* tDCS/MRI contraindications, including: pregnancy, ferrous metal in any part of the body, serious medical conditions, claustrophobia, metallic implants, skin damage, conditions such as eczema at electrode sites, cranial pathologies

Where this trial is running

Sacramento, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.