Effects of Blood Flow Restriction Training on Grip Strength

Restrict and Strengthen: Unraveling the Impact of Blood Flow Restriction Training on Upper Extremity Grip Strength

Not applicable Interventional Casa Colina Hospital and Centers for Healthcare · NCT06535373

This study is testing if a special exercise method that restricts blood flow can improve grip strength in healthy young adults better than regular low-weight training.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 35 Years
SexAll
SponsorCasa Colina Hospital and Centers for Healthcare Academic / other
Locations1 site (Pomona, California)
Trial IDNCT06535373 on ClinicalTrials.gov

What this trial studies

This study investigates how Blood Flow Restriction (BFR) training affects grip strength in healthy young adults compared to traditional low-weight resistance training. BFR training involves using a device to partially restrict blood flow to muscles during exercise, allowing for strength gains with lower weights. The research aims to fill a gap in existing literature by focusing specifically on upper extremity grip strength, which is vital for daily activities and sports performance. By examining the safety and efficacy of this training method, the study seeks to provide valuable insights for optimizing grip performance and rehabilitation.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy young adults aged 18 to 35 with no significant health issues.

Not a fit: Patients with cardiovascular, musculoskeletal, or neurological disorders, or those taking certain medications, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance rehabilitation strategies and sports training by providing an effective method to improve grip strength with lower resistance.

How similar studies have performed: While BFR training has shown success in various populations, this specific application to grip strength is relatively novel and under-researched.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants must be between 18 and 35 years old at the time of enrollment.

Participants should be in good general health with no known cardiovascular, musculoskeletal, or neurological disorders that could interfere with exercise participation.

Participants must provide informed consent before enrollment in the study, indicating their willingness to participate voluntarily.

Exclusion Criteria:

* Participants with a history of cardiovascular disease (e.g., heart disease, hypertension), musculoskeletal injuries (e.g., fractures, dislocations), or neurological disorders (e.g., neuropathy) that could affect exercise performance will be excluded.

Participants taking medications or supplements that may impact muscle strength, metabolism, or blood flow will be excluded from the study.

Pregnant individuals will be excluded due to potential risks associated with exercise and blood flow restriction during pregnancy.

Individuals with recent upper extremity injuries, such as strains, sprains, or fractures, will be excluded until fully recovered.

Blood Pressure: Participants with uncontrolled high blood pressure or other medical conditions affecting vascular health may be excluded due to potential risks associated with blood flow restriction.

Where this trial is running

Pomona, California

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy Volunteers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.