Effects of Blood Flow Restriction Training on Elbow Ligament Thickness

Outcomes of Blood Flow Restriction Training on the Ulnar Collateral Ligament

Not applicable Interventional The Methodist Hospital Research Institute · NCT06664827

This study is testing if low-intensity exercises with blood flow restriction can make the elbow ligament thicker and stronger in healthy volunteers.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorThe Methodist Hospital Research Institute Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT06664827 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the impact of blood flow restriction (BFR) training on the ulnar collateral ligament (UCL) in healthy volunteers. Participants will engage in low-intensity resistance exercises with BFR twice a week for eight weeks, focusing on changes in ligament thickness and joint space laxity in the dominant arm. The study will assess arm strength and use sonography to measure ligament characteristics before and after the intervention. The goal is to determine if BFR exercises can enhance ligament properties and strength.

Who should consider this trial

Good fit: Ideal candidates are healthy volunteers aged 18-50 who can commit to the exercise program.

Not a fit: Patients with current or recent injuries to the hand, elbow, or shoulder, or those with vascular issues will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective training methods for improving ligament health and strength in healthy individuals.

How similar studies have performed: While the specific application of BFR in this context is novel, there is existing research indicating potential benefits of BFR training in various populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy volunteer
* Agree to complete all exercise sessions and program in its entirety
* Between the ages of 18-50 years old

Exclusion Criteria:

* Current or recent injury of the hand, elbow, or shoulder
* Outside of the ages of 18-50 years old
* Vascular compromise or previous vascular surgery
* History of DVT
* Current participation in other BFR research study
* Currently participating in a structured strength training program
* Any musculoskeletal conditions resulting in inability to exercise
* Participants may not be collegiate/professional baseball/softball players
* Vulnerable populations

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HealthyHealthy Male and Female SubjectsHealthy Volunteers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.