Effects of bladder training and pelvic floor exercises with Botox on urinary symptoms

Effect of Bladder Training and Pelvic Floor Exercise Training on Urinary Symptoms and Quality of Life in Patients With Overactive Bladder Syndrome

Not applicable Interventional Hacettepe University · NCT06209333

This study is testing if adding bladder training and pelvic floor exercises to Botox treatment can help people with Overactive Bladder Syndrome feel better compared to just getting Botox alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorHacettepe University Academic / other
Drugs / interventionsradiation
Locations1 site (Ankara)
Trial IDNCT06209333 on ClinicalTrials.gov

What this trial studies

This study examines the impact of combining bladder training and pelvic floor exercise with Botulinum Toxin-A (BTx-A) treatment in patients suffering from Overactive Bladder Syndrome (OABS) who have not responded to conservative therapies. Participants will be divided into two groups: one receiving BTx-A along with the additional training and the other receiving only BTx-A with standard education. The study aims to evaluate urinary symptoms and quality of life before and after treatment at specified intervals. The goal is to determine if the combined approach leads to better outcomes than BTx-A alone.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with non-neurogenic Overactive Bladder Syndrome who have not responded to conservative treatments.

Not a fit: Patients with neurogenic bladder issues, pregnant women, or those with certain anatomical abnormalities will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve urinary symptoms and quality of life for patients with OABS.

How similar studies have performed: While similar approaches have been explored, this specific combination of interventions is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* over the age of 18 (those with a Mini Mental Test score of 24 and above for individuals over the age of 65),
* Who has Non-Neurogenic Overactive Bladder Syndrome,
* Patients who received Routine Botulinum Toxin-A administration because they did not respond to conservative treatment,
* Patients who volunteer to participate in the study will be included.

Exclusion Criteria:

* Patients with Neurogenic Overactive Bladder Syndrome,
* Pregnant Women,
* Lack of cooperation in evaluation and/or treatment and lack of literacy status,
* Patients with urogynocological/anatomical abnormalities,
* Patients receiving pelvic radiation therapy,
* Patients with psychiatric or neurogenic disorders and
* Patients who have not given consent to the study and do not have an informed consent form (BGOF).

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Overactive Bladder Syndromepelvic floor exercisebladder trainingstandard patient educationbotulinum toxin-ABTx-A
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.