Effects of bariatric surgery and exercise on muscle health
Exploring the Short-Term Effect of Bariatric Surgery on Muscle Structure And Function; Followed By A Feasibility Assessment Of Exercise Intervention Post Bariatric Surgery
This study is testing how bariatric surgery affects muscle health in obese adults and whether adding exercise after surgery helps improve their muscle strength and function.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 12 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | University of Nottingham Academic / other |
| Locations | 1 site (Derby) |
| Trial ID | NCT05569785 on ClinicalTrials.gov |
What this trial studies
This project aims to evaluate how bariatric surgery impacts muscle structure and function in obese adults. It is a feasibility study conducted at the Royal Derby Hospital, where 12 patients will be assessed before and after surgery. Following surgery, participants will be randomly assigned to either a Resistance Exercise Training group or a standard care group for a 4-week period. The study will span a total of 13-14 weeks, focusing on the integration of exercise post-surgery.
Who should consider this trial
Good fit: Ideal candidates are obese adults aged 18-70 with a BMI of 35 kg/m2 or higher, scheduled for bariatric surgery.
Not a fit: Patients with a BMI of 60 or higher or those deemed unfit for surgery will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance recovery and muscle health in patients undergoing bariatric surgery.
How similar studies have performed: While the specific combination of bariatric surgery and exercise interventions is less common, similar studies have shown positive outcomes in muscle health post-surgery.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Obese adults (BMI greater than or equal to 35 kg/m2) * Age range 18-70 years old * Scheduled for RYGB surgery or sleeve gastrectomy surgery. * Ability to give informed consent Exclusion Criteria: * Patients who are not fit or not suitable for RYGB or Sleeve Gastrectomy as per Tier 4 Bariatric Surgery MDT. * For those high-risk patients who are fast tracked to surgery, we will exclude patients with a NYHA \>3 or 4 heart failure status and those with end stage renal failure. * BMI greater than or equal to 60
Where this trial is running
Derby
- Comap — Derby, United Kingdom (Recruiting)
Study contacts
- Study coordinator: Iskandar Idris
- Email: iskandar.idris@nottingham.ac.uk
- Phone: 01332724605
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.