Effects of balance and cognitive training on patients with multiple sclerosis
Combined Effects of Balance and Cognitive Training on Executive Functions, Balance and Quality of Life in Patients With Multiple Sclerosis
This study tests if adding brain exercises to balance training can help people with multiple sclerosis improve their thinking skills, balance, and overall quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 42 (estimated) |
| Ages | 40 Years to 55 Years |
| Sex | All |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Lahore) |
| Trial ID | NCT06845722 on ClinicalTrials.gov |
What this trial studies
This study investigates how combined balance and cognitive training can improve executive functions, balance, and quality of life in patients with multiple sclerosis. It involves a randomized controlled trial with 42 participants aged 40-55, who will be divided into two groups. Both groups will receive balance training, while one group will also undergo cognitive training twice a week for 12 weeks. The effectiveness of the interventions will be assessed using the Montreal Cognitive Assessment and the Berg Balance Scale.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40-55 with diagnosed multiple sclerosis who experience balance and cognitive impairments.
Not a fit: Patients with severe cognitive impairments from other neurological disorders or those with active major psychiatric illnesses may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance mobility and cognitive function in patients with multiple sclerosis, improving their overall quality of life.
How similar studies have performed: Previous studies have shown promising results with cognitive and balance training in similar patient populations, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age of the patients should be 40-55 years.(20) * Gender: both males and females * Patients with diagnosed multiple sclerosis. * According to MOCA assessment, patients with scoring 21-25 will be included. (Patients with executive function deficits due to Multiple Sclerosis including relapsing-remitting, primary progressive and secondary progressive MS).(21) * Patients feel difficulty in Impaired Balance and walking. * According to the Berg Balance Scale, patients under 21-45 will be included.(22) Exclusion Criteria: * Participants with a history of moderate to severe head injury, stroke and seizures will be excluded(23) * Cognitive impairment due to presence of current or past neurological disorders other than Multiple Sclerosis will be excluded.(23) * Participants with active major psychiatric illness (such as schizophrenia, bipolar disorder or depressive disorder) will be excluded(23) * Patients with history of learning disabilities, severe head trauma, alcohol or drug abuse will be excluded(23)
Where this trial is running
Lahore
- Jinnah Hospital — Lahore, Pakistan (Recruiting)
Study contacts
- Principal investigator: Sabiha Arshad M.Phill — Riphah International University
- Study coordinator: Imran Amjad
- Email: imran.amjad@riphah.edu.pk
- Phone: 03324390125
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.