Effects of Astaxanthin on cognitive performance in active women

Impact of Astaxanthin on Cognition in Recreationally Active Females

Phase 4 Interventional University of North Alabama · NCT06460181

This study tests if taking Astaxanthin can help active women think better and feel less mentally tired during physical or mental challenges.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years to 39 Years
SexFemale
SponsorUniversity of North Alabama Academic / other
Locations1 site (Florence, Alabama)
Trial IDNCT06460181 on ClinicalTrials.gov

What this trial studies

This study investigates the potential benefits of Astaxanthin, a natural antioxidant, on cognitive performance in recreationally active females experiencing mental fatigue. Participants will undergo a four-week supplementation period with either Astaxanthin or a placebo, followed by assessments of cognitive performance after a mental fatigue protocol. The study aims to determine if Astaxanthin can help maintain cognitive function during prolonged physical or mental exertion, which is crucial for athletes and active individuals. The research builds on previous findings in older populations, focusing on younger, active women.

Who should consider this trial

Good fit: Ideal candidates are healthy, recreationally active females aged 18-39 who meet specific physical activity guidelines.

Not a fit: Patients who are not recreationally active or have medical conditions that affect cognitive performance may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a dietary intervention to help active women maintain cognitive performance during mentally demanding activities.

How similar studies have performed: While previous studies have shown Astaxanthin's benefits in older populations, this approach in younger, active individuals is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The participant population will be healthy, recreationally active females between the ages of 18-39 without any medical conditions. To be deemed recreationally active, they must meet the World Health Organization minimum activity guidelines of completing at least 150 to 300 min moderate-intensity activity or 75-150 min of vigorous-intensity activity a week, plus muscle-strengthening activities 2 or more days a week.
* Adult females with a stable body weight (± 5 lbs.) for 2 months
* Adult females with a normal menstrual cycle
* Adult females not on a low-carb, high-fat diet or intermittent fasting
* Adult females who are not pregnant of actively attempting to become pregnant

Exclusion Criteria:

\-

Where this trial is running

Florence, Alabama

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mental Fatigue
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.