Effects of anxiety on satisfaction during cataract surgery

Pain, Anxiety and Anesthetic Satisfaction for Patient With Different State Anxiety Underwent Cataract Surgery With Topical Anesthesia

Not applicable Interventional National Taiwan University Hospital · NCT06826417

This study tests how anxiety affects pain and satisfaction during cataract surgery and whether taking Xanax before the procedure can help improve comfort for patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment400 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorNational Taiwan University Hospital Academic / other
Locations1 site (Taipei, Taiwan)
Trial IDNCT06826417 on ClinicalTrials.gov

What this trial studies

This study investigates how different levels of anxiety affect pain and satisfaction during cataract surgery performed under topical anesthesia. Patients will complete anxiety questionnaires before receiving either Xanax or a placebo thirty minutes prior to surgery. After the procedure, their pain levels and satisfaction with anesthesia will be assessed, with follow-up evaluations the next day. The goal is to understand the relationship between anxiety traits and the effectiveness of pharmacological interventions to enhance patient comfort during surgery.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 80 diagnosed with cataracts and scheduled for phacoemulsification surgery under topical anesthesia.

Not a fit: Patients with contraindications for surgery or medication, or those who do not experience preoperative anxiety, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management of anxiety and pain for patients undergoing cataract surgery, enhancing their overall surgical experience.

How similar studies have performed: Previous studies have shown varying success with oral anxiolytics in surgical settings, indicating potential for this approach but also highlighting the need for further investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age between 18 and 80 years old.
2. Patients diagnosed with cataracts.
3. Scheduled for cataract surgery with phacoemulsification and intraocular lens implantation under surface anesthesia at National Taiwan University Hospital.
4. No adverse reactions to oral anti-anxiety medication (XANAX).

Exclusion Criteria:

1. Presence of any contraindications for surgery before the procedure.
2. Presence of any contraindications for medication before the procedure.
3. Inability to provide clear and complete answers to relevant questionnaires, or expression of no preoperative anxiety during the outpatient visit, or scores below 21 on the STAI-S or STAI-T assessment.
4. Regular use of anti-anxiety medications, sleeping pills, or analgesics before the procedure.
5. Pregnancy or breastfeeding during the preoperative period.
6. Severe corneal diseases, overripe cataracts, small pupils, or lens dislocation leading to difficulties in conventional surgery.
7. Patients under surface anesthesia who cannot fully cooperate with the surgical procedure.
8. Pregnant or uncertain pregnancy status (women under 55 years old to be verbally asked by research team members).

Where this trial is running

Taipei, Taiwan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Oral AnxiolyticPhacoemulsificationCataract SurgerySatisfaction SurveyState AnxietyOral anxiolyticCataract surgerySatisfaction survey
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.