Effects of aerobic exercise with blood flow restriction on COPD patients

Exploring the Effects of Aerobic Exercise Combined with Blood Flow Restriction Training on Exercise Capacity, Cardiopulmonary Functions, and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease

Not applicable Interventional National Cheng Kung University · NCT06756646

This study is testing if adding blood flow restriction to aerobic exercise can help people with COPD breathe better and exercise more easily.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment90 (estimated)
Ages30 Years to 85 Years
SexAll
SponsorNational Cheng Kung University Academic / other
Locations1 site (Tainan, Taiwan)
Trial IDNCT06756646 on ClinicalTrials.gov

What this trial studies

This study investigates how combining aerobic exercise with blood flow restriction training can improve cardiopulmonary function and exercise capacity in patients with Chronic Obstructive Pulmonary Disease (COPD). It addresses the complications associated with COPD, such as cardiovascular disorders and muscle atrophy, which often lead to decreased physical activity. By incorporating blood flow restriction training into a structured exercise program, the research aims to enhance exercise tolerance and overall quality of life for these patients. The findings could provide insights into a novel rehabilitation strategy for managing COPD.

Who should consider this trial

Good fit: Ideal candidates include individuals with stable COPD classified as levels 2-4 who have not participated in rehabilitation programs recently.

Not a fit: Patients with severe cardiovascular disease, recent hospitalizations, or those dependent on oxygen supply may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve exercise capacity and quality of life for patients with COPD.

How similar studies have performed: While blood flow restriction training is a relatively novel approach, preliminary studies have shown promising results in improving muscle strength and exercise capacity in various populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. COPD classified as levels 2-4.
2. Stable condition without worsening in the past three months.
3. No participation in any rehabilitation program within the past six months.
4. Ability to understand and follow verbal commands and cooperate with an exercise training program.

Exclusion Criteria:

1. Unconscious or unable to cooperate with the evaluator.
2. Hospitalization due to acute illness within the past three months.
3. Severe joint diseases or history of lower limb surgery.
4. Severe cardiovascular disease (e.g., presence of a cardiac pacemaker or acute myocardial infarction within the past six months).
5. Dependence on oxygen supply.

Where this trial is running

Tainan, Taiwan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Obstructive Pulmonary DiseaseBlood flow restriction training
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.