Effects of aerobic exercise with blood flow restriction on COPD patients
Official title: Exploring the Effects of Aerobic Exercise Combined With Blood Flow Restriction Training on Exercise Capacity, Cardiopulmonary Functions, and Quality of Life in Patients With Chronic Obstructive Pulmonary Disease
Run by National Cheng Kung University · NCT06756646 · Data updated 2026-11-12
This study is testing if adding blood flow restriction to aerobic exercise can help people with COPD breathe better and exercise more easily.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 85 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | National Cheng Kung University Academic / other |
| Locations | 1 site (Tainan, Taiwan) |
| Status | Recruiting |
| Started | November 20, 2024 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2030 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT06756646 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with stable COPD classified as levels 2-4 who have not participated in rehabilitation programs recently.
✕Probably not a fit
Patients with severe cardiovascular disease, recent hospitalizations, or those dependent on oxygen supply may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates how combining aerobic exercise with blood flow restriction training can improve cardiopulmonary function and exercise capacity in patients with Chronic Obstructive Pulmonary Disease (COPD). It addresses the complications associated with COPD, such as cardiovascular disorders and muscle atrophy, which often lead to decreased physical activity. By incorporating blood flow restriction training into a structured exercise program, the research aims to enhance exercise tolerance and overall quality of life for these patients. The findings could provide insights into a novel rehabilitation strategy for managing COPD.
Why it matters
Potential benefit: If successful, this approach could significantly improve exercise capacity and quality of life for patients with COPD.
How similar studies have gone: While blood flow restriction training is a relatively novel approach, preliminary studies have shown promising results in improving muscle strength and exercise capacity in various populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. COPD classified as levels 2-4. 2. Stable condition without worsening in the past three months. 3. No participation in any rehabilitation program within the past six months. 4. Ability to understand and follow verbal commands and cooperate with an exercise training program. Exclusion Criteria: 1. Unconscious or unable to cooperate with the evaluator. 2. Hospitalization due to acute illness within the past three months. 3. Severe joint diseases or history of lower limb surgery. 4. Severe cardiovascular disease (e.g., presence of a cardiac pacemaker or acute myocardial infarction within the past six months). 5. Dependence on oxygen supply.
Where it's running
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National Cheng Kung University Hostipal
Tainan, Taiwan, Taiwan Recruiting
Study contacts
- Principal investigator: Kun-Ling Tsai, Ph.D. — Department of Physical Therapy, National Cheng Kung University
- Study coordinator: Kun-Ling Tsai, Ph.D.
- Email: kunlingtsai@mail.ncku.edu.tw
- Phone: 886-6-2353535
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.