Effects of acupuncture on Parkinson's disease patients with chronic appendicitis
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis: a Single-center, Randomized, Double-blind Study
This study is testing if acupuncture can help people with Parkinson's disease who also have chronic appendicitis feel better by easing their symptoms, especially those related to digestion.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 40 Years to 70 Years |
| Sex | All |
| Sponsor | The First Affiliated Hospital of University of Science and Technology of China Academic / other |
| Locations | 1 site (Hefei, Anhui) |
| Trial ID | NCT06304285 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of acupuncture on patients suffering from Parkinson's disease who also have chronic appendicitis. It aims to assess whether acupuncture can alleviate both motor and non-motor symptoms associated with Parkinson's disease, particularly focusing on gastrointestinal issues. The intervention includes both acupuncture and sham acupuncture treatments to evaluate the efficacy of the approach. The study is based on previous findings that suggest a connection between intestinal health and Parkinson's symptoms.
Who should consider this trial
Good fit: Ideal candidates include Parkinson's disease patients experiencing bradykinesia and chronic appendicitis.
Not a fit: Patients with cognitive disorders not related to Parkinson's disease or those with severe neuropsychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the quality of life for Parkinson's disease patients by alleviating their symptoms through acupuncture.
How similar studies have performed: Previous studies have shown promising results for acupuncture in treating non-motor symptoms of Parkinson's disease, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients presenting with bradykinesia, combined with resting tremor and/or myotonia. * Appendix CT suggested chronic appendicitis evaluated by two experienced experts. * All subjects and their guardians give informed consent to the content of this study and sign informed consent. * Normal coagulation function. * If the patient had taken oral anti-PD drugs, it had been stable for at least 2 weeks at enrollment. Exclusion Criteria: * Treatment with dopamine blockers or dopamine depleters in doses and time courses consistent with drug-induced parkinsonism. * Neuroimaging examination of presynaptic dopaminergic system function was normal. * Patients who had suffered severe brain trauma or underwent complex craniotomy within 5 years prior to enrollment. * Cognitive disorders that are not on the Parkinson's spectrum, such as Alzheimer's disease, frontotemporal dementia, and Niemann-Pick disease, have been diagnosed. * People diagnosed with severe neuropsychiatric disorders (epilepsy, bipolar disorder, major depressive episode, etc.) according to DSM-V. * Complicated with serious systemic diseases, disorders of consciousness, stroke, serious coronary heart disease, diabetes, liver and kidney diseases, and serious visual and hearing disorders. * Patients with severe organic or functional dysphagia;Those who were deemed by the researcher to be unable to complete the visit and auxiliary examination as required by the study protocol.
Where this trial is running
Hefei, Anhui
- The First Affiliated Hospital of University of Science and Technology of China — Hefei, Anhui, China (Recruiting)
Study contacts
- Study coordinator: Yuhua Chen, M.M.S.
- Email: yh1215@mail.ustc.edu.cn
- Phone: +8615955236270
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.