Effects of a supplement on sperm quality in men

To Investigate Supplements for Improving Male Sperm Quality and Combating Aging

Not applicable Interventional Kaohsiung Veterans General Hospital. · NCT06339996

This study is testing a new supplement to see if it can improve sperm quality in men who have been diagnosed with poor sperm health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages30 Years to 50 Years
SexMale
SponsorKaohsiung Veterans General Hospital. Academic / other
Locations1 site (Kaohsiung City)
Trial IDNCT06339996 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of a new male supplement on sperm quality in men diagnosed with poor sperm quality. Fifty participants will receive the supplement for three months, after which their semen will be analyzed to assess changes in sperm quality, mitochondrial function, and sexual function. The study also aims to evaluate symptoms of aging using standardized scales before and after the treatment period. By focusing on the relationship between supplementation and sperm health, this research addresses a growing concern related to male fertility.

Who should consider this trial

Good fit: Ideal candidates are men with poor sperm quality who do not meet the WHO criteria for normal semen analysis and have a BMI between 18-30 kg/m2.

Not a fit: Patients with azoospermia, varicocele, chromosome anomalies, malignancies, or those using hormone therapy or supplements in the past three months may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve sperm quality and overall reproductive health in men with fertility issues.

How similar studies have performed: While various supplements have been tested for improving sperm quality, this specific approach is novel and has not been extensively studied.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Not meet the criteria of the 6th edition of the WHO manual for human semen analysis
* BMI:18-30 kg/m2

Exclusion Criteria:

* Azoospermia
* Varicocele
* Chromosome anomaly
* Malignancy
* Using hormone therapy or supplements in recent 3 months

Where this trial is running

Kaohsiung City

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Unrecognized ConditionMale supplementSperm qualityAgingMitochondrial functionSexual function
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.