Effectiveness of Complex Decongestive Therapy for Venous Insufficiency

Experimental Study on the Efficacy of Complex Decongestive Therapy (CDT) Treatment in Patients With Venous Insufficiency

Not applicable Interventional University of Salamanca · NCT06231940

This study is testing if Complex Decongestive Therapy combined with exercise can help people with venous insufficiency feel better and improve their blood flow compared to just doing exercises alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment21 (estimated)
Ages35 Years to 75 Years
SexAll
SponsorUniversity of Salamanca Academic / other
Locations1 site (Salamanca)
Trial IDNCT06231940 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of Complex Decongestive Therapy (CDT) in improving venous flow and alleviating symptoms in patients with venous insufficiency. It employs a simple blind randomized design, where one group receives CDT along with a lower limb exercise program, while a control group participates in exercises alone. The study aims to assess not only the primary effects of CDT on venous flow but also secondary outcomes such as symptom relief, quality of life improvements, and any adverse effects. A total of 21 adult participants with specific classifications of venous insufficiency will be enrolled, with careful exclusion of those with certain health conditions.

Who should consider this trial

Good fit: Ideal candidates are adults aged 35 to 75 with mild to moderate venous insufficiency classified as C1 to C4 on the CEAP scale.

Not a fit: Patients with acute cardiac, hepatic, or renal diseases, as well as those currently undergoing CDT treatment, may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could significantly improve the quality of life and symptom management for patients suffering from venous insufficiency.

How similar studies have performed: Previous studies have shown promising results for similar therapeutic approaches, suggesting potential efficacy for CDT in managing venous insufficiency.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 35 and 75 years
* Presence of mild venous insufficiency, moderate or severe (grades C1, C2, C3, and C4 on the Clinical, Etiologic, Anatomic, Pathophysiologic \[CEAP\] scale).

Exclusion Criteria:

* Subjects affected by uncompensated acute cardiac, hepatic, and renal disease, acute obstructive vascular disease, acute trauma, primary lymphedema, and acute skin infections.
* Patients who are currently receiving complex decongestive therapy treatment or in the last six months.

Where this trial is running

Salamanca

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lymphatic EdemaCellulitis of LegVein Diseaseconservative treatmentVenous InsufficiencyComplex decongestive therapy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.