Effectiveness of ACT for problematic chemsex

Effectiveness of a Group Intervention Based on Acceptance and Commitment Therapy to Address Problematic Chemsex Through a Randomized Clinical Trial

Not applicable Interventional Universidad Europea de Madrid · NCT06406296

This study tests whether an online therapy called Acceptance and Commitment Therapy can help people struggling with problematic chemsex behaviors feel better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment22 (estimated)
Ages18 Years and up
SexAll
SponsorUniversidad Europea de Madrid Academic / other
Locations1 site (Villaviciosa De Odón, Madrid)
Trial IDNCT06406296 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the efficacy of Acceptance and Commitment Therapy (ACT) as a psychological intervention for individuals experiencing problematic chemsex behaviors. Participants will undergo an 8-session online-delivered ACT treatment, with assessments conducted through self-report instruments before and after the intervention, as well as at a 3-month follow-up. The study includes a control group to compare outcomes and ensure the validity of the results.

Who should consider this trial

Good fit: Ideal candidates are Spanish-speaking adults over 18 who have used psychoactive substances to enhance sexual experiences and experience significant discomfort related to their sexual practices.

Not a fit: Patients currently receiving psychological or psychopharmacological treatment, or those with intellectual disabilities or serious mental disorders, may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve the mental health and sexual well-being of individuals struggling with problematic chemsex behaviors.

How similar studies have performed: While there is limited data on ACT specifically for chemsex, similar therapeutic approaches have shown promise in treating compulsive sexual behaviors in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* older than 18 years-old
* Spanish speaking
* having used psychoactive substances to facilitate, maintain and/or improve sexual relations in the last year
* significant score on the HBI Inventory (of 53 or more)
* clinically significant discomfort related to sexual practices
* degree of interference in his/her life of sexual practices greater than or equal to 5 out of 10
* desire to improve/reduce excessive sexual behaviour

Exclusion Criteria:

* receiving psychological or psychopharmacological treatment
* intellectual disability
* substance dependence (use not associated with sex)
* personality disorder or other serious or chronic mental disorder diagnosed

Where this trial is running

Villaviciosa De Odón, Madrid

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HypersexualityCompulsive Sexual BehaviorSexualized Drug UseSexualityRisky sexual behavior
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.