Effect of Vibration Therapy on Sarcopenia in Knee Osteoarthritis Patients
Randomized Control Trial Investigating the Effectiveness of Vibration Therapy on Sarcopenia in Osteoarthritis Knee Patients
This study is testing if vibration therapy can help improve muscle strength and mobility in people with knee osteoarthritis and low muscle mass who are preparing for knee replacement surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 45 Years and up |
| Sex | All |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT03880344 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of vibration therapy in patients suffering from knee osteoarthritis, particularly focusing on those with sarcopenia. It aims to address the decline in muscle strength and functionality that often accompanies end-stage osteoarthritis, which can lead to increased disability and longer recovery times post-surgery. Participants will undergo vibration therapy alongside physiotherapy to assess improvements in muscle strength and overall mobility. The study will include patients scheduled for total knee replacement and will evaluate their progress through various assessments.
Who should consider this trial
Good fit: Ideal candidates are males and females over 45 years old with end-stage knee osteoarthritis scheduled for total knee replacement.
Not a fit: Patients with connective tissue disorders, myositis, or those with a history of substance abuse may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance recovery and improve quality of life for patients with knee osteoarthritis by addressing muscle atrophy.
How similar studies have performed: While there is ongoing research into vibration therapy, this specific application for sarcopenia in knee osteoarthritis patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female patients aged over 45 with end stage knee OA * Patient has been scheduled for TKR * Able to comply with the assessments and has given oral and written consent Exclusion Criteria: * Patients with connective tissue disorders or myositis condition * Previous cases of alcoholism or drug abuse * Pregnancy or breast feeding
Where this trial is running
Hong Kong
- Department of Orthopaedics & Traumatology — Hong Kong, Hong Kong (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.