Effect of treatments for tubal ectopic pregnancy on ovarian reserve
The Effect of Different Treatment Modalities of Tubal Ectopic Pregnancy on Ovarian Reserve: a Prospective Cohort Study
This study is trying to see how different treatments for tubal ectopic pregnancy affect the hormone levels related to ovarian reserve in women aged 18-44.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 44 Years |
| Sex | Female |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Trial ID | NCT06471166 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess how different treatment modalities for tubal ectopic pregnancy impact ovarian reserve, specifically measuring levels of the AMH hormone. Patients aged 18-44 with a confirmed or suspected diagnosis of tubal ectopic pregnancy will be included, while those with certain exclusion criteria will be omitted. The study will monitor hormonal changes following treatment to determine any effects on ovarian function.
Who should consider this trial
Good fit: Ideal candidates are women aged 18-44 with a diagnosis or suspicion of tubal ectopic pregnancy.
Not a fit: Patients who have used hormonal contraceptives recently or have undergone previous surgeries on their fallopian tubes or ovaries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into preserving ovarian reserve in women undergoing treatment for ectopic pregnancy.
How similar studies have performed: While the specific approach of this study may be novel, similar studies have explored the impact of ectopic pregnancy treatments on reproductive health, showing varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The study will include patients aged 18-44 years with known diagnosis or suspicion of diagnosis of tubal ectopic pregnancy (abnormal doubling rates of their b-HCG levels as well as ultrasonographically identified or unidentified gestational sacs outside the uterus) * Included patients must have capacity to provide informed consent. Given the potential emergent nature of presentation, women will not be recruited if fully informed consent could be compromised due to a highly distressed emotional state or significant hemorrhage necessitating the need for urgent surgery Exclusion Criteria: 1. The use of hormonal contraceptives within two months of enrolment 2. If other surgery was conducted at the time of salpingectomy. 3. If a woman was pregnant at follow up visit for AMH measurement 4. History of previous surgeries of fallopian tubes and/or ovaries
Where this trial is running
Asyut
- Assiut university — Asyut, Egypt (Recruiting)
Study contacts
- Study coordinator: Andro Bahgat, MD
- Email: androbahgat7@gmail.com
- Phone: 01283104773
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.