Effect of Tramadol on Sore Throat After Thyroid Surgery
Effect of Tramadol on Postoperative Sore Throat in Thyroid Surgery Under General Anesthesia With Endotracheal Intubation: A Randomized Controlled Trial
This study tests whether giving tramadol can help reduce sore throat pain after thyroid surgery for patients who have been under general anesthesia.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 168 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Sponsor | Affiliated Cancer Hospital of Shantou University Medical College Academic / other |
| Locations | 1 site (Shantou, Guangdong) |
| Trial ID | NCT04991493 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of tramadol on postoperative sore throat in patients undergoing thyroid surgery with general anesthesia and endotracheal intubation. It is a prospective, randomized, controlled trial conducted at a single university hospital. A total of 168 patients will be randomly assigned to receive either tramadol or normal saline before and during surgery to assess the effectiveness of tramadol in alleviating sore throat symptoms postoperatively.
Who should consider this trial
Good fit: Ideal candidates for this study are female patients with ASA physical status I-II scheduled for elective thyroidectomy with endotracheal intubation.
Not a fit: Patients with a history of thyroid surgery, chronic sore throat, or contraindications to tramadol will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide an effective method to reduce postoperative sore throat discomfort for patients undergoing thyroid surgery.
How similar studies have performed: Other studies have explored the use of tramadol for postoperative pain management, indicating potential success in similar approaches.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Female with American Society of Anesthesiologists (ASA) physical status I-II; Elective thyroidectomy(non-endoscopic) with endotracheal intubation; The patient signed the consent form. Exclusion Criteria: \- History of thyroid surgery A history of preoperative sore throat; Pregnancy; Retrosternal goiter; Thyroid tumor invading trachea need trachea reconstruction; Potentially difficult airway; Clinical diagnosis of chronic sore throat; Clinical diagnosis of psychosis; Tracheotomy after operation； Transfer to intensive care unit after operation； Contraindications to tramadol； Body mass index (BMI) \> 30kg/m\^2.
Where this trial is running
Shantou, Guangdong
- Affiliated Cancer Hospital of Shantou University Medical College Medical — Shantou, Guangdong, China (Recruiting)
Study contacts
- Principal investigator: zegeng su, master — Affiliated Cancer Hospital of Shantou University Medical College Medical
- Study coordinator: zegeng su, master
- Email: goctor@163.com
- Phone: 13929688978
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.