Effect of surgical position on kidney stone removal success
Does the Positioning in Retrograde Intrarenal Surgery Affect Stone-Free Rates? A Prospective Randomized Controlled Trial
This study tests whether changing the way patients are positioned during kidney stone surgery can help doctors remove stones more successfully and with fewer complications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 128 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ondokuz Mayıs University Academic / other |
| Locations | 1 site (Samsun) |
| Trial ID | NCT06809582 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how the surgical position during retrograde intrarenal surgery (RIRS) influences the success rate of removing kidney stones in adults. Participants will be randomly assigned to either a standard lithotomy position or a modified lithotomy position, which includes a 30-degree Trendelenburg tilt. The study aims to compare stone-free rates and complication rates between the two positions after the procedure. Follow-up imaging will be conducted to evaluate the effectiveness of the surgical approach.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with single or multiple kidney stones measuring 2 cm or less.
Not a fit: Patients with severe cardiovascular disease, congenital kidney anomalies, or active urinary tract infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical techniques and higher success rates in kidney stone removal.
How similar studies have performed: While there is limited data on this specific comparison, similar studies have explored surgical positioning in urology with varying results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Presence of single or multiple kidney stones, with the largest stone ≤2 cm * Age ≥18 years * Provided written informed consent to participate in the study * Indicated for retrograde intrarenal surgery (RIRS) as a treatment approach Exclusion Criteria: * Severe cardiovascular disease (e.g., heart failure) * Congenital kidney anomalies (e.g., horseshoe kidney, ectopic kidney) * Concurrent ureteral stones * Pregnancy or planning pregnancy * History of previous kidney surgery on the same side * Active urinary tract infection (UTI) * Coagulopathy or use of anticoagulant therapy that cannot be stopped before surgery
Where this trial is running
Samsun
- Ondokuz Mayıs University — Samsun, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Murat Gulsen — Ondokuz Mayıs University
- Study coordinator: Murat Gulsen
- Email: mglotr@gmail.com
- Phone: +905062357421
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.