Effect of strengthening staple lines on nausea and vomiting after sleeve gastrectomy

The Effect of Staple Line Reinforcement Procedures on Postoperative Nausea and Vomiting in Sleeve Gastrectomy

NA · Sakarya University · NCT06151912

This study is testing if strengthening the staple lines during sleeve gastrectomy can help reduce nausea and vomiting after surgery for patients undergoing this weight loss procedure.

Quick facts

PhaseNA
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorSakarya University (other)
Locations1 site (Sakarya, Adapazarı)
Trial IDNCT06151912 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the impact of staple line reinforcement procedures on postoperative nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy. It involves two surgical techniques: one surgeon will suture the staple line while another will apply fibrin glue to enhance its strength. The study aims to assess the effectiveness of these interventions in reducing complications such as bleeding and leakage, which are critical concerns in bariatric surgery. The trial will take place from June 2023 to June 2024 at Sakarya University.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with a body mass index of 40 kg/m2 and above who are scheduled for laparoscopic sleeve gastrectomy.

Not a fit: Patients with a history of hiatal hernia, gastritis, ulcers, or previous gastrointestinal surgeries will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce the incidence of postoperative nausea and vomiting, improving recovery and quality of life for bariatric surgery patients.

How similar studies have performed: While the approach of staple line reinforcement is commonly practiced, this specific study's focus on its effect on postoperative nausea and vomiting is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with a body mass index of 40 kg/m2 and above

Exclusion Criteria:

* Patients with hiatal hernia, gastritis or ulcer detected during endoscopy
* Smoker
* Patients who have previously had another bariatric procedure
* Patients who have previously undergone gastrointestinal system surgery
* Patients with any contraindications for bariatric surgery

Where this trial is running

Sakarya, Adapazarı

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Bariatric Surgical Procedures, Nausea, Postoperative, Vomiting, Postoperative

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.