Effect of shock wave therapy on blood flow in diabetes
Monitoring Effect Of Shock Wave On Microcirculation Changes In Type2 Diabetes Mellitus
NA · South Valley University · NCT06159192
This study tests if shock wave therapy can improve blood flow and nerve function in people with type 2 diabetes and nerve damage.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | South Valley University (other) |
| Locations | 2 sites (Luxor, South Valley University and 1 other locations) |
| Trial ID | NCT06159192 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of low-intensity extracorporeal shock wave therapy on nitric oxide synthase and microcirculation in patients with type 2 diabetes mellitus and peripheral neuropathy. The therapy aims to enhance nerve repair and regeneration by promoting neurotrophic factors and activating Schwann cells. Participants will receive this treatment while maintaining their current pharmacological regimen, allowing researchers to monitor changes in nerve function and blood flow. The study focuses on understanding how this novel approach can improve symptoms associated with diabetic neuropathy.
Who should consider this trial
Good fit: Ideal candidates are individuals with type 2 diabetes mellitus who are symptomatically stable and have peripheral neuropathy.
Not a fit: Patients with implanted cardiac pacemakers, skin allergies, or other specified cardiovascular conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this therapy could significantly improve nerve function and circulation in patients with diabetic neuropathy.
How similar studies have performed: While the use of shock wave therapy is gaining interest, this specific application in diabetic neuropathy is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients have to be symptomatically stable with type 2 diabetes mellitus complicated with peripheral neuropathy. * Optimized pharmacological treatment that will be remained unchanged throughout the study. Exclusion Criteria: * Implanted cardiac pacemakers. * Patients with known skin allergies. * Presence of skin inflammations. * Peripheral vascular disease. * Patients with unstable angina pectoris. * Progressive ventricular dysrhythmia. * Intermittent claudication.
Where this trial is running
Luxor, South Valley University and 1 other locations
- South Valley University — Luxor, South Valley University, Egypt (RECRUITING)
- South Valley University — Luxor, South Valley University, Egypt (RECRUITING)
Study contacts
- Study coordinator: ibrahim ismail ibrahim abuzaid, PHD
- Email: ibrahim_ismail_2011@svu.edu.eg
- Phone: +201006512150
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Shock Wave and Nitric Oxide, Shock Wave, Ntric oxide, Diabetes mellitus, Nerve conduction velocity