Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Effect of reducing tooth occlusion on pain after root canal treatment

Official title: Influence of Occlusal Reduction on Endodontic Postoperative Pain: a Randomized Clinical Trial

Run by University of Jordan · NCT06977009 · Data updated 2026-11-12

This study is testing if changing how your teeth fit together after a root canal can help reduce pain for people with infected or previously treated teeth.

More Post Operative Pain trials

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment60 (estimated)
SponsorUniversity of Jordan
Academic / other
Locations1 site (Amman, Amman Governorate)
StatusRecruiting
StartedFebruary 28, 2025
Main results expectedJuly 1, 2025
Study endsJuly 20, 2025
Registry record updatedMay 16, 2025
Trial IDNCT06977009 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are systemically healthy individuals aged 18 to 70 with necrotic pulp in posterior molars requiring root canal treatment.

Probably not a fit

Patients with significant medical conditions, bruxism, or those who have taken pain-altering medications prior to the procedure may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates how occlusal reduction affects post-operative pain following single-visit root canal treatments in patients with necrotic pulps or previously accessed teeth. Conducted at the postgraduate endodontic clinic at Jordan University Hospital, participants will be randomly assigned to either receive occlusal reduction or maintain their occlusion after treatment. The study aims to determine if altering occlusal contacts can lead to reduced pain levels post-treatment. The intervention involves precise adjustments made by trained postgraduate students using specialized dental equipment.

Why it matters

Potential benefit: If successful, this approach could significantly reduce post-operative pain for patients undergoing root canal treatments.

How similar studies have gone: While the specific approach of occlusal reduction in this context may be novel, similar studies have shown varying degrees of success in managing post-operative pain through different interventions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Systemically healthy subjects (ASA I\&II) between the age of 18 and 70 years
2. Patients diagnosed with necrotic pulp or previously initiated (accessed).
3. Posterior maxillary or mandibular molar tooth.
4. Presence of an opposing tooth (or teeth) with normal occlusal contact with the opposing tooth (or teeth).
5. Tooth needs cuspal coverage.

Exclusion Criteria:

1. Pregnant females.
2. Patients with significant medical conditions (ASA III \& IV).
3. Reported bruxism or clenching.
4. Took analgesics\\antibiotics or other drugs that might alter their pain during the last 12 hours preoperatively.
5. A history of allergic reactions to any of the medications and/or materials used.
6. Patients with a tooth that had no contacts or premature contact, fewer than three teeth on one side of the jaw.
7. Greater than grade I mobility or pocket depth greater than 5mm.
8. Non-restorable crowns, severely curved root canals, or post-treatment endodontic disease were, also, excluded.

Where it's running

  • Jordan university hospital
    Amman, Amman Governorate, Jordan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.