Effect of Progesterone Levels on Pregnancy Outcomes in Infertile Women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between serum progesterone levels on the day of the β-hCG test and ongoing pregnancy rates in women undergoing artificial cycles. It includes a prospective cohort of infertile patients who receive luteal phase support with vaginal natural progesterone. The study aims to determine if lower serum progesterone levels on the day of the pregnancy test correlate with higher miscarriage rates, despite positive pregnancy tests. The goal is to identify a cut-off point for progesterone levels that could predict pregnancy outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The subject must provide written informed consent prior to any study related procedures
* Women ≤50 years old
* BMI ≤ 35 kg/m2
* Adequate endometrial thickness (\>6.5mm) and pattern (Triple A structure) in the proliferative phase

Exclusion Criteria:

* Uterine Pathology, adnexal pathology
* Systemic diseases

Where it's running

• IVI RMA Valencia
  Valencia, Valencia, Spain Recruiting

Study contacts

• Study coordinator: Laura Caracena, Msr
• Email: LAURA.CARACENA@IVIRMA.COM
• Phone: 034 963 050 900

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• AI into Ultrasound Diagnostics in Reproductive Medicine

  Researchers are testing AI tools that analyze transvaginal ultrasound images to help detect endometriosis, adenomyosis, uterine masses, and pregnancy-related receptivity in women aged 18-45.

  Recruiting Semmelweis University · Budapest, Budapest · NCT07810920

• Tadalafil to increase uterine lining and improve frozen embryo transfer success

  This test sees if adding daily tadalafil to standard estrogen helps women with unexplained infertility using good-quality day‑5 frozen embryos get a thicker uterine lining and better transfer outcomes.

  Recruiting Phase 4 Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07499804

• FET-LET-2x2: Testing natural vs medicated natural cycles for frozen embryo transfer

  This study tests four approaches to preparing the uterus for frozen embryo transfer to see which yields the best pregnancy rate in women undergoing IVF.

  Recruiting University of Novi Sad · Novi Sad · NCT07425990

• Integrative care guided by biological aging markers for unexplained female infertility

  This trial tests whether measuring telomeres and other biological aging markers can guide a personalized integrative treatment to help women aged 25–42 with persistent unexplained infertility improve their chances of pregnancy.

  Recruiting BEYOND GENOMiX SA, AG, Ltd · Neuchâtel · NCT07404969

• How fitness, heart health, and mental well-being relate to assisted fertility treatments

  This study tries to see if physical activity, cardiorespiratory fitness, cardiovascular health, sleep, and stress affect pregnancy chances for women undergoing assisted fertility treatments.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT07321665

• How attitudes toward artificial intelligence relate to anxiety and quality of life in women receiving infertility treatment

  This study will test whether women's attitudes toward artificial intelligence are linked to their anxiety and quality of life while undergoing infertility treatment.

  Recruiting Acibadem University · Istanbul, Ataşehir · NCT07308561

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.