Effect of Oxidized Regenerated Cellulose on Vestibular Sulcus Depth after Clark Vestibuloplasty
Official title: The Effect of Using Oxidized Regenerated Cellulose Material in Addition to the Standard Clark Vestibuloplasty Technique on Increasing Vestibular Sulcus Depth
Run by Izmir Katip Celebi University · NCT07767682 · Data updated 2026-11-12
This study tests whether adding oxidized regenerated cellulose to Clark vestibuloplasty helps deepen the vestibular sulcus and improve comfort for adults with shallow vestibular depth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Izmir Katip Celebi University Academic / other |
| Locations | 1 site (Izmir, Çiğli) |
| Status | Recruiting |
| Started | April 9, 2026 |
| Main results expected | June 30, 2027 |
| Study ends | July 30, 2027 |
| Registry record updated | August 17, 2026 |
| Trial ID | NCT07767682 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) who are systemically healthy, non-smokers, have insufficient vestibular sulcus depth, are not pregnant, and have no prior vestibuloplasty in the same region.
✕Probably not a fit
Patients who smoke, have systemic disease, take regular medications, are pregnant or lactating, or have had vestibuloplasty in the same area may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will compare Clark vestibuloplasty with oxidized regenerated cellulose (ORC) to standard Clark vestibuloplasty with a periodontal dressing in adults with insufficient vestibular sulcus depth. Participants will be assigned to one of two groups and followed for 3 months, with measurements of vestibular sulcus depth and keratinized gingival tissue taken at baseline, 1 month, and 3 months after surgery. Postoperative pain and analgesic use will be recorded during the first 7 days. The study aims to determine if ORC provides additional depth and comfort compared with the traditional approach.
Why it matters
Potential benefit: If successful, the ORC approach could improve vestibular depth and patient comfort after surgery.
How similar studies have gone: Prior vestibuloplasty studies suggest feasibility of ORC in oral surgery, but evidence for this specific combination is limited and exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Systemically healthy * Non-smoker * Insufficient vestibular sulcus depth * No regular medication use * Age 18 years or older * No previous vestibuloplasty in the same region * Not pregnant or breastfeeding * Willing to participate and able to provide written informed consent Exclusion Criteria: * Presence of a systemic disease * Regular use of systemic medication * Pregnancy or lactation * Smoking or alcohol use * Previous vestibuloplasty in the same region
Where it's running
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İzmir Katip Çelebi University
Izmir, Çiğli, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Can Berk Arığ
- Email: canberkarig@gmail.com
- Phone: +90 534 060 64 57
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.