Effect of Orofacial Pain Therapy on Bruxism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study assesses how well gnathological splints work to reduce bruxism and clenching in adults with temporomandibular dysfunction and masticatory myofascial pain. Participants will be monitored with a 24-hour portable device that records masticatory muscle activity to establish daytime and nighttime cut-offs. The goal is to see if wearing a splint correlates with decreased muscle activity during wakefulness and sleep. The study is conducted at the Università Cattolica del Sacro Cuore in Rome under the Catholic University of the Sacred Heart, with no listed external collaborators. Eligibility requires informed consent and a clinical indication for splint therapy; changes in medication during monitoring are excluded to avoid confounding effects on pain or muscle activity.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Adult subjects
* Subjects who agree to sign the informed consent form
* Patients with temporomandibular dysfunction who are indicated for treatment with a gnathological splint

Exclusion criteria:

\- Patients who change their medication regimen during the monitoring period because pharmacological therapy may affect facial pain and/or muscle activity.

Where it's running

• Università Cattolica del Sacro Cuore
  Roma, Italy Recruiting

Study contacts

• Study coordinator: Anna Alessandri Bonetti
• Email: anna.alessandribonetti@unicatt.it
• Phone: +393341413280

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  This study will test whether diffusion MRI can detect differences in the jaw muscles of adults with masticatory myofascial pain syndrome.

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• Masticatory Muscle Activity with a 24-Hour Wearable Device

  This study tests whether real-world jaw muscle activity relates to stress and parafunctional habits in people with chronic masticatory myofascial pain compared with healthy controls using a wearable EMG device.

  Recruiting Midwestern University · Downers Grove, Illinois · NCT07861906

• Occlusal splint and masseter Botox effects on jaw and neck muscles

  We will test whether a custom jaw splint, Botox injections into the masseter muscles, or both, can change head and neck muscle activity in adults with myofascial pain syndrome.

  Recruiting Phase 4 Istanbul University · Istanbul, Vezneciler · NCT07082972

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.