Effect of modified poco-poco exercise on frailty in elderly
Effect of Modified Poco-Poco Exercise to Frailty Stages, Expression of Global DNA Methylation, GDF15 and Lamin A COP on Elderly Living On Community in Bandung
This study tests if a special exercise program can help frail older adults in Indonesia feel stronger and healthier.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 17 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | Universitas Padjadjaran Academic / other |
| Locations | 1 site (Bandung, West Java) |
| Trial ID | NCT06628895 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of a modified poco-poco exercise program on frail elderly individuals in Bandung, Indonesia. Participants will engage in a multicomponent exercise regimen that includes flexibility, balance, aerobic, and strengthening exercises three times a week for 12 weeks. The study aims to assess changes in global DNA methylation levels, GDF15, and Lamin A COP, as well as overall frailty levels among participants. The findings could provide insights into the relationship between exercise and aging biomarkers in the elderly population.
Who should consider this trial
Good fit: Ideal candidates for this study are frail elderly individuals aged 60-64 living in Bandung with a MoCA INA score above 18.
Not a fit: Patients with severe cognitive impairments, musculoskeletal disorders, or significant cardiovascular diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could improve physical health and reduce frailty in elderly patients, enhancing their quality of life.
How similar studies have performed: Other studies have shown positive outcomes with multicomponent exercise interventions for frail elderly populations, suggesting this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Frailty level is in pre-frailty 2. MoCA INA score above 18 3. Domicile in Bandung City 4. Willing to participate in the study after informed consent Exclusion Criteria: 1. There is a hearing impairment that may prevent the subject from receiving verbal instructions 2. There is uncorrected visual impairment 3. There are musculoskeletal disorders so that they cannot perform exercise procedures or procedures for measuring research variables 4. Subjects received other rehabilitation programs 5. Post-stroke with average limb muscle strength below three 6. There are diseases that cause impaired cognition such as Alzheimer\'s disease, traumatic head injury, Parkinson\'s disease. 7. There are severe joint diseases such as osteoarthritis and rheumatoid arthritis that may worsen during exercise or may cause difficulty in carrying out the exercise program. 8. Severe cardiovascular disease as assessed by a heart and vascular specialist 9. Unable to attend Exercises regularly
Where this trial is running
Bandung, West Java
- Puskesmas Sekejati — Bandung, West Java, Indonesia (Recruiting)
Study contacts
- Study coordinator: Istingadah Desiana, dr, SpKFR, Ger(K), FIPM (USG)
- Email: istingadah.desiana@unpad.ac.id
- Phone: 62 812 7123 9200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.