Effect of Mastoid Condition on Endoscopic Cholesteatoma Management

The Impact of Mastoid Condition and Ossicular Reconstruction on the Outcome of the Transcanal Endoscopic Management of Localized Atticoantral Cholesteatoma Patients

NA · Sohag University · NCT06246682

This study is testing how the health of the mastoid bone and different ways to rebuild hearing bones affect the success of endoscopic surgery for people with a specific type of ear condition called cholesteatoma.

Quick facts

PhaseNA
Study typeInterventional
Enrollment25 (estimated)
Ages12 Years and up
SexAll
SponsorSohag University (other)
Locations1 site (Sohag)
Trial IDNCT06246682 on ClinicalTrials.gov

What this trial studies

This interventional study aims to investigate how the condition of the mastoid process and the method of ossicular reconstruction influence the outcomes of transcanal endoscopic management in patients with localized atticoantral cholesteatoma. It focuses on patients with primary acquired cholesteatoma, assessing the effectiveness of endoscopic removal techniques. The study will evaluate various factors, including the presence of symptoms and the extent of the cholesteatoma, to determine optimal management strategies.

Who should consider this trial

Good fit: Ideal candidates for this study are patients aged 12 years and older with primary acquired localized atticoantral cholesteatoma.

Not a fit: Patients with congenital or secondary acquired cholesteatoma, extensive, residual, or recurrent cholesteatoma, or craniofacial anomalies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve surgical outcomes and hearing restoration for patients with cholesteatoma.

How similar studies have performed: While there have been studies on cholesteatoma management, this specific approach focusing on mastoid condition and endoscopic techniques is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients presenting with primary acquired localized atticoantral cholesteatoma.

Exclusion Criteria:

* Age group: patients below 12 years old.
* Patients presenting with congenital or secondary acquired cholesteatoma.
* Patients presenting with extensive, residual, or recurrent cholesteatoma.
* Patients with craniofacial anomalies.

Where this trial is running

Sohag

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cholesteatoma of Attic, Cholesteatoma, Middle Ear, cholesteatoma, Endoscopic ear surgery, mastoid process

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.