Effect of light therapy on blood pressure in people with hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the acute effects of full-body photobiomodulation (PBM) and modified intravascular laser irradiation of blood (ILIB) on blood pressure and vascular health in individuals diagnosed with hypertension. It involves a randomized, double-blind, sham-controlled design with 48 participants aged 40 to 60 years, who have been on hypertension medication for at least three months. Participants will be divided into four groups to receive either effective or sham treatments, and their blood pressure, endothelial function, and arterial stiffness will be assessed before and after the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Sedentary or irregularly inactive individuals (IPAQ)
* Both sexes
* Age between 40 to 60 years old
* Clinical diagnosis of hypertension for at least 3 months with difficulty in blood pressure control
* Hypertension classification up to stage 2
* Individuals who have a prescription for hypertension control drugs and have been using these drugs for at least 3 months

Exclusion Criteria:

* Diabetes diagnosis
* Smokers
* BMI \> 30 kg/m²
* Cardiac pacemaker use
* Presence of arrhythmias or other decompensated cardiovascular diseases
* Musculoskeletal, orthopedic or neurological conditions that make it unable to participate in the procedures
* Presence of cognitive deficits that make it difficult to understand the assessments
* Presence of active neoplasia, under suspicion or after 5 years in remission period
* Presence of tattoos (covering a large body area, or the anterior wrist region)
* Photosensitive drugs use
* Pregnant women or under suspicion
* Presence of epilepsy or seizures
* Participants who present a systolic blood pressure ≥ 180 mmHg and/or diastolic blood pressure ≥ 110 mmHg on the day of the intervention

Where it's running

• Federal University of São Carlos
  São Carlos, São Paulo, Brazil Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.