Effect of light therapy on blood pressure in people with hypertension
Acute Effect of Photobiomodulation on Blood Pressure, Endothelial Function and Arterial Stiffness in Individuals with Hypertension: a Randomized Controlled Trial
NA · Universidade Federal de Sao Carlos · NCT06678698
This study is testing whether light therapy can help lower blood pressure in people with high blood pressure who are already on medication.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 48 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | Universidade Federal de Sao Carlos (other) |
| Locations | 1 site (São Carlos, São Paulo) |
| Trial ID | NCT06678698 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the acute effects of full-body photobiomodulation (PBM) and modified intravascular laser irradiation of blood (ILIB) on blood pressure and vascular health in individuals diagnosed with hypertension. It involves a randomized, double-blind, sham-controlled design with 48 participants aged 40 to 60 years, who have been on hypertension medication for at least three months. Participants will be divided into four groups to receive either effective or sham treatments, and their blood pressure, endothelial function, and arterial stiffness will be assessed before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are sedentary individuals aged 40 to 60 years with a clinical diagnosis of hypertension and difficulty in blood pressure control.
Not a fit: Patients with diabetes, obesity, or significant cardiovascular issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a non-invasive treatment option to help manage hypertension effectively.
How similar studies have performed: While the approach of using photobiomodulation is relatively novel, similar studies have shown promising results in other conditions, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Sedentary or irregularly inactive individuals (IPAQ) * Both sexes * Age between 40 to 60 years old * Clinical diagnosis of hypertension for at least 3 months with difficulty in blood pressure control * Hypertension classification up to stage 2 * Individuals who have a prescription for hypertension control drugs and have been using these drugs for at least 3 months Exclusion Criteria: * Diabetes diagnosis * Smokers * BMI \> 30 kg/m² * Cardiac pacemaker use * Presence of arrhythmias or other decompensated cardiovascular diseases * Musculoskeletal, orthopedic or neurological conditions that make it unable to participate in the procedures * Presence of cognitive deficits that make it difficult to understand the assessments * Presence of active neoplasia, under suspicion or after 5 years in remission period * Presence of tattoos (covering a large body area, or the anterior wrist region) * Photosensitive drugs use * Pregnant women or under suspicion * Presence of epilepsy or seizures * Participants who present a systolic blood pressure ≥ 180 mmHg and/or diastolic blood pressure ≥ 110 mmHg on the day of the intervention
Where this trial is running
São Carlos, São Paulo
- Federal University of São Carlos — São Carlos, São Paulo, Brazil (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hypertension, hypertension, photobiomodulation, low-level light therapy