Effect of Isokinetic Strengthening Training on Stroke and Joint Replacement Patients
Comparison of the Functional Recovery and Cytokines Changes Between Isokinetic and Isotonic Training in Patients With Acute Stroke, After Total Hip Replacement or After Total Knee Replacement
This study is testing whether a special type of strength training can help people who recently had a stroke or joint replacement feel better and improve their health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 126 (estimated) |
| Ages | 40 Years to 70 Years |
| Sex | All |
| Sponsor | Taichung Veterans General Hospital Academic / other |
| Locations | 1 site (Taichung City) |
| Trial ID | NCT02938416 on ClinicalTrials.gov |
What this trial studies
This study involves 83 participants, including patients within one month of stroke and those who have undergone total hip or knee replacement surgery. Participants will be randomly assigned to one of three training groups: isokinetic, isotonic, or isometric strengthening exercises. The study will measure various outcomes such as peak torque of hip and knee, quality of life, and other health indicators before and after a four-week training program. Statistical analysis will determine the effectiveness of isokinetic training compared to the other methods.
Who should consider this trial
Good fit: Ideal candidates include individuals who have experienced a stroke within the past month or have had total hip or knee replacement surgery within the last two to four weeks.
Not a fit: Patients who are unable to perform basic movements like sitting to standing or have significant comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance rehabilitation outcomes for patients recovering from stroke and joint replacement surgeries.
How similar studies have performed: Previous studies have shown positive outcomes with similar strengthening approaches, indicating potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * within one month of acute stroke * receive total hip/knee replacement within two to four weeks before Exclusion Criteria: * cannot perform from sitting to standing * Body Mass Index \> 30 * Lower limbs fracture history * Diabetic polyneuropathy * Cardiopulmonary diseases that impede exercise prescription * Impaired cognitive function * Infectious disease during the study period that may cause cytokine changes
Where this trial is running
Taichung City
- Department of Physical Medicine and Rehabilitation — Taichung City, Taiwan (Recruiting)
Study contacts
- Principal investigator: Yuan-Yang Cheng, MD, PhD — Department of Physical Medicine and Rehabilitation
- Study coordinator: Yuan-Yang Cheng, MD, PhD
- Email: rifampin@gmail.com
- Phone: +886-4-23592525
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.