Effect of Injection Speed on Local Anesthetic Spread in ESPB

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates how different injection speeds affect the distribution of local anesthetic during ultrasound-guided erector spinae plane block (ESPB) in patients undergoing CT-guided lung nodule localization. Seventy-four patients are randomly assigned to receive either a fast injection (30 ml in 30 seconds) or a slow injection (30 ml in 180 seconds) of local anesthetic. The study aims to determine if the speed of injection influences the effectiveness of the anesthetic spread. The methodology includes ultrasound guidance for precise needle placement and monitoring of anesthetic distribution via CT imaging post-procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients scheduled for CT-guided lung nodule localization under local anesthesia will be selected

1. aged 18-80 years
2. BMI 18-30 kg/m²
3. ASA classification I-III

Exclusion Criteria:

1. Allergy to the study drug or to local anesthetics
2. History of opioid abuse
3. Previous infection at the ESPB or PVB puncture site
4. Peripheral neuropathy
5. Dysfunction of blood coagulation

Where it's running

• Nanjing First Hospital
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Tao Shan
• Email: shantao2021@163.com
• Phone: +8618852095135

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Nerve block to treat severe belly pain in the emergency department

  This study tests whether injecting anesthesia into the erector spinae plane can relieve non-surgical abdominal pain in the ED without relying on narcotics.

  Recruiting Early Phase 1 University of California, Irvine · Orange, California · NCT07826936

• Cervical ESPB to help pain after proximal humerus repair

  This study tests whether a cervical erector spinae plane block helps manage postoperative pain after surgery to fix a proximal humeral fracture in adults under general anesthesia.

  Recruiting Menoufia University · Shibīn al Kawm, Menoufia · NCT07824466

• Single-level vs two-level erector spinae plane block for breast surgery

  This study tests whether a single-level ESPB provides similar pain relief to a two-level ESPB for adults undergoing breast surgery.

  Recruiting Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · Yenimahalle, Ankara · NCT07747623

• Midpoint transverse process to pleura block vs erector spinae plane block for thoracic herpes zoster pain

  This study compares two ultrasound-guided nerve blocks to see which better eases pain from thoracic herpes zoster in adults 21–60.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07732556

• Continuous ESP Block for Analgesia After CABG Surgery

  This trial tests whether a continuous erector spinae plane (ESP) block with ropivacaine, delivered via catheter and patient-controlled analgesia, provides better postoperative pain relief than placebo in patients undergoing coronary artery bypass grafting.

  Recruiting Phase 3 Instituto do Coracao · São Paulo, São Paulo · NCT07666178

• External Oblique Intercostal Plane Block vs Erector Spinae Plane Block for Paediatric Upper Abdominal Surgeries

  This study tests whether two ultrasound-guided nerve blocks—external oblique intercostal plane and erector spinae plane—provide different pain relief for children undergoing upper abdominal surgery.

  Recruiting Alexandria University · Alexandria · NCT07617545

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.