Effect of Injection Speed on Local Anesthetic Spread in ESPB
Impact of Different Injection Rate on Local Anaesthetic Spread of Ultrasound-guided Erector Spinae Plane Block
This study is testing whether injecting local anesthetic quickly or slowly affects how well it spreads for patients getting a procedure to locate lung nodules.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 74 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Nanjing First Hospital, Nanjing Medical University Academic / other |
| Locations | 1 site (Nanjing, Jiangsu) |
| Trial ID | NCT06936904 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how different injection speeds affect the distribution of local anesthetic during ultrasound-guided erector spinae plane block (ESPB) in patients undergoing CT-guided lung nodule localization. Seventy-four patients are randomly assigned to receive either a fast injection (30 ml in 30 seconds) or a slow injection (30 ml in 180 seconds) of local anesthetic. The study aims to determine if the speed of injection influences the effectiveness of the anesthetic spread. The methodology includes ultrasound guidance for precise needle placement and monitoring of anesthetic distribution via CT imaging post-procedure.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-80 scheduled for CT-guided lung nodule localization under local anesthesia.
Not a fit: Patients with allergies to local anesthetics, history of opioid abuse, or certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the effectiveness of local anesthesia during lung procedures, potentially improving patient comfort and outcomes.
How similar studies have performed: While similar studies on injection techniques exist, this specific investigation into injection speed and its effects on ESPB is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients scheduled for CT-guided lung nodule localization under local anesthesia will be selected 1. aged 18-80 years 2. BMI 18-30 kg/m² 3. ASA classification I-III Exclusion Criteria: 1. Allergy to the study drug or to local anesthetics 2. History of opioid abuse 3. Previous infection at the ESPB or PVB puncture site 4. Peripheral neuropathy 5. Dysfunction of blood coagulation
Where this trial is running
Nanjing, Jiangsu
- Nanjing First Hospital — Nanjing, Jiangsu, China (Recruiting)
Study contacts
- Study coordinator: Tao Shan
- Email: shantao2021@163.com
- Phone: +8618852095135
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.