Effect of High-Intensity Interval Training on Metabolic Syndrome in Women with Central Obesity

Response Of Metabolic Syndrome Severity Score To High Intenisty Interval Training In Women With Central Obesity.

Not applicable Interventional Cairo University · NCT06509464

This study is testing if high-intensity interval training can help women aged 25 to 45 with central obesity improve their metabolic health compared to a diet plan.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment48 (estimated)
Ages25 Years to 45 Years
SexFemale
SponsorCairo University Academic / other
Locations1 site (Giza)
Trial IDNCT06509464 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of high-intensity interval training (HIIT) on the metabolic syndrome severity score in women aged 25 to 45 with central obesity. A total of 48 participants will be randomly assigned to either a HIIT group or a caloric restriction diet group for six weeks. The study will evaluate changes in physical fitness and metabolic health through various assessments, including the Modified Harvard Step test and laboratory investigations of blood glucose and lipid profiles. The goal is to determine the effectiveness of HIIT in improving metabolic health outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 25 to 45 with central obesity and a waist-height ratio between 49-58.

Not a fit: Patients with uncontrolled diabetes, hypertension, cognitive impairments, severe anemia, physical disabilities, pregnancy, or recent cardiothoracic surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new exercise-based intervention for improving metabolic health in women with central obesity.

How similar studies have performed: Other studies have shown positive outcomes with high-intensity interval training for metabolic health, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- 1. 48 Women subjects with age ranges from 25to 45 years.

2\. Waist height ratio ranges from 49-58 (overweight and seriously overweight).

Exclusion Criteria:

* 1\. Uncontrolled Diabetes 2. Uncontrolled hypertension 3. Cognitive impaired patients 4. Severe Anemic women 5. Subjects with physical or musculoskeletal disabilities 6. Pregnancy 7. Recent cardiothoracic surgery

Where this trial is running

Giza

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Metabolic SyndromMetabolic syndrom severity scoreMetabolic syndromCentral obesity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.