Effect of high-definition brain stimulation on non-suicidal self-injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of high-definition transcranial alternating current stimulation (HD-tACS) on patients aged 12-18 who engage in non-suicidal self-injury (NSSI). Forty participants diagnosed with NSSI will receive either active or sham HD-tACS treatment over a week, with assessments conducted before and after the intervention. The study aims to explore the underlying neural mechanisms of NSSI using magnetic resonance imaging (MRI) alongside neuropsychological evaluations. Participants will be randomized to ensure the reliability of results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

The patients were diagnosed by 2 or more senior clinical psychiatrists, meeting DSM-V criteria, and having 1 or more non-suicidal self-injurious behaviors in the last 6 months.

12-18 years of age.

The medicine has not changed in the 4 weeks prior to or after this study, and if it has to be changed, the treatment medication is required to be at a subtherapeutic dosage level.

Exclusion Criteria:

The patient has suicidal ideation or has committed suicidal behavior

T1 or T2 weighted phase magnetic resonance images show focal brain lesions

patients had neurological disorders such as epilepsy, or serious physical illnesses

patients had a history of substance abuse and drug dependence in the last 6 months or use of anticonvulsant drugs in the last 3 months

patients had received radial cranial electrical stimulation or magnetic stimulation treatment in the last 3 months or received electroconvulsive therapy in the last 6 months

patients had previous significant head trauma or EEG abnormality in the last 1 month

body-mounted devices unsuitable for treatment, such as pacemakers, artificial valves, and other metal implants.

Where it's running

• Anhui Medical University
  Hefei, Anhui, China Recruiting

Study contacts

• Study coordinator: Kai Wang, PhD
• Email: wangkai1964@126.com
• Phone: +86-0551-62923704

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Alternating electrical brain stimulation for Lewy body dementia

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.