Effect of fermented millet porridge on gut health and inflammation in women
Effect of Fermented Millet Porridge on Gut Microbiota Diversity and Inflammation Markers in Women of Reproductive Age in Rural Burkina Faso: A Pilot Study
This study is testing if eating fermented millet porridge can improve gut health and reduce inflammation in women of reproductive age living in rural Burkina Faso.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 49 Years |
| Sex | Female |
| Sponsor | Institut de Recherche en Sciences de la Sante, Burkina Faso Government |
| Locations | 1 site (Bobo-Dioulasso, Houet, Région Des hauts-Bassins) |
| Trial ID | NCT05299970 on ClinicalTrials.gov |
What this trial studies
This study investigates how fermented millet porridge affects gut microbiota diversity, short chain fatty acid levels, and inflammation markers in women of reproductive age living in rural Burkina Faso. It aims to address maternal undernutrition by exploring a traditional food processing method, fermentation, to enhance nutrient content. Participants will consume the porridge and their health metrics will be monitored over the study period. The research focuses on a population that is often overlooked in nutritional interventions.
Who should consider this trial
Good fit: Ideal candidates are women aged 18 to 49 living in rural Burkina Faso who do not have allergies to pearl millet and are not on antibiotic treatment.
Not a fit: Patients who are outside the age range, have serious illnesses affecting their diet, or have allergies to pearl millet will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve gut health and reduce inflammation in women, potentially enhancing maternal and child health outcomes.
How similar studies have performed: While there is limited data on similar interventions in this specific population, traditional fermented foods have been associated with positive health outcomes in various cultures.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Participant are * 18 to 49 years old * Resident in the study area and do not plan to move within 5 months following the start of the study * Are not on antibiotic treatment on inclusion and have not been in the previous 3 weeks. * Do not suffer from any pathology that could interfere with their diet. * Have no known allergy to pearl millet or its derivatives * Agree to sign a consent to participate in the study- Exclusion Criteria: * Women under 18 or over 49 * Women not consuming pearl millet porridge due to allergy or food preference * Women planning to move from the study area within 5 months of the start of the study * Women with serious illnesses that may interfere with their diet * Women on antibiotic treatment or at the time of inclusion or having been in the previous 3 weeks. * In addition, women who will benefit from antibiotic therapy during the study will be excluded from the analysis
Where this trial is running
Bobo-Dioulasso, Houet, Région Des hauts-Bassins
- Irss-Dro — Bobo-Dioulasso, Houet, Région Des hauts-Bassins, Burkina Faso (Recruiting)
Study contacts
- Principal investigator: Laeticia C TOE — Irss-Dro
- Study coordinator: Laeticia C TOE, MD
- Email: cellaety@yahoo.fr
- Phone: 0022671007272
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.