Effect of Electrical Stimulation on Knee Osteoarthritis

Investigation of the Effect of Superimposed Neuromuscular Electrical Stimulation With Active Contraction in Patients With Knee Osteoarthritis.

Not applicable Interventional Gulhane School of Medicine · NCT06277570

This study is testing if a new type of electrical stimulation combined with regular physiotherapy can help people with knee osteoarthritis feel better and improve their physical function.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment63 (estimated)
Ages40 Years to 65 Years
SexAll
SponsorGulhane School of Medicine Academic / other
Locations1 site (Ankara, Etlik)
Trial IDNCT06277570 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of superimposed neuromuscular electrical stimulation combined with active contraction on patients suffering from knee osteoarthritis. It aims to assess improvements in physical function, muscle and joint structure, and overall quality of life. The approach involves using non-invasive electrical stimulation to activate muscles and potentially alleviate symptoms associated with knee osteoarthritis. Participants will receive conventional physiotherapy alongside this innovative treatment to evaluate its effectiveness.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 40-65 with grade 2-3 knee osteoarthritis.

Not a fit: Patients with severe osteoarthritis in other joints or those with contraindications for electrotherapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve physical function and quality of life for patients with knee osteoarthritis.

How similar studies have performed: Previous studies have shown promising results with neuromuscular electrical stimulation in managing knee osteoarthritis symptoms, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Having grade 2-3 knee osteoarthritis according to Kellgren and Lawrence Classification,
* Being between the ages of 40-65, ,
* Being literate
* Volunteer

Exclusion Criteria:

* Having Grade 2 or higher osteoarthritis in the hip, ankle, or foot joint Presence of a history of knee-related surgery (arthroplasty, meniscectomy, etc.)
* Having a deformity in the waist, leg, hip, knee, or ankle
* Having any inflammatory rheumatic, neurological, vestibular, cardiopulmonary disease
* Having active knee joint synovitis
* BMI\>40
* Having a condition that is contraindicate for electrotherapy (malignancy, pacemaker, epilepsy, deep vein thrombosis, loss of protective sensation, etc.)
* Having received physiotherapy in the last 3 months
* Being diagnosed with a psychiatric disease
* Having a cooperation problem that makes it difficult to comply with evaluation and treatment

Where this trial is running

Ankara, Etlik

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Knee OsteoarthritisElectric Stimulation Therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.