Effect of early invasive treatment in elderly patients with high-risk heart conditions
Comparison of Mortality and Complication Rates (Re-myocardial Infarction, Heart Failure, Re-hospitalization, Stroke) After 12 Months Between Two Groups of Patients Undergoing Early Invasive and Late Invasive Strategies in Patients With Elderly Patients With High - Risk Non-ST-segment Elevation Acute Coronary Syndrome.
This study is testing whether older patients with serious heart issues do better with early treatment compared to later treatment, looking at their health outcomes over a year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 385 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | Gia Dinh People Hospital Academic / other |
| Locations | 1 site (Ho Chi Minh City) |
| Trial ID | NCT06486233 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare major adverse cardiovascular events (MACE) and their predisposing factors in elderly patients with high-risk non-ST-segment elevation acute coronary syndrome who receive either early or late invasive treatment. It seeks to answer two key questions: the factors associated with a late invasive strategy and whether there is a significant difference in mortality and complication rates between the two treatment groups after 12 months. The study will involve patients aged 60 and older who meet specific criteria for high-risk conditions and receive reperfusion intervention.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients aged 60 years and older diagnosed with high-risk non-ST-segment elevation acute coronary syndrome.
Not a fit: Patients with acute coronary syndrome due to stent thrombosis or coronary artery bypass graft occlusion may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for elderly patients with high-risk heart conditions, potentially reducing mortality and complications.
How similar studies have performed: Other studies have explored similar approaches in treating acute coronary syndromes, but the specific focus on elderly patients and the comparison of early versus late invasive strategies is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged 60 years and older * high - risk non-ST-segment elevation acute coronary syndrome (according to the 2023 European Heart Association recommended standards). * receives reperfusion intervention. Exclusion Criteria: * Acute coronary syndrome due to stent thrombosis, or coronary artery bypass graft occlusion. * Incomplete medical records.
Where this trial is running
Ho Chi Minh City
- Gia Dinh people hospital — Ho Chi Minh City, Vietnam (Recruiting)
Study contacts
- Study coordinator: Sang Thanh Nguyen, Doctor
- Email: drsangthanhnguyen@gmail.com
- Phone: +84902489252
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.